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Sigma-Aldrich

Lithium L-lactate

≥98% (titration)

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Synonym(s):
(S)-2-Hydroxypropionic acid lithium salt, L-Lactic acid lithium salt, Sarcolactic acid lithium salt
Empirical Formula (Hill Notation):
C3H5LiO3
CAS Number:
27848-80-2
Molecular Weight:
96.01
Beilstein:
6127244
EC Number:
248-692-5
MDL number:
MFCD00065512
PubChem Substance ID:
57654325
NACRES:
NA.25

Quality Level

200

Assay

≥98% (titration)

form

powder

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

impurities

<2% water (Karl Fischer)

color

white

solubility

water: 100 mg/mL, clear, colorless

cation traces

Li: 5.26-9.30% (anhydrous)

application(s)

food and beverages
hematology
microbiology

storage temp.

2-8°C

SMILES string

[Li+].C[C@H](O)C([O-])=O

InChI

1S/C3H6O3.Li/c1-2(4)3(5)6;/h2,4H,1H3,(H,5,6);/q;+1/p-1/t2-;/m0./s1

InChI key

GKQWYZBANWAFMQ-DKWTVANSSA-M

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General description

Lithium L-lactate, also known as Sarcolactic acid lithium or Lithium (S)-2-hydroxypropanoate, is a lithium salt of L-lactic acid, the optically active isomer of lactic acid characterized by an (S) stereochemical arrangement. L-Lactic acid is naturally produced in animals through the fermentation of pyruvate via lactate dehydrogenase during normal metabolism and exercise. This compound is a crucial element in lactic acid fermentation carried out by lactic acid bacteria, where carbohydrates are converted into lactic acid. In humans, lactic acid and its conjugate base play vital roles in various biological processes, spanning from prenatal development to the maintenance of the extracellular fluid surrounding neurons.

Recent research indicates that Lithium L-lactate exhibits mood-stabilizing effects, particularly in individuals with bipolar disorder. This impact is believed to be linked to its influence on the phosphatidylinositol (PI) pathway and the inhibition of glycogen synthase kinase-3 (GSK-3) activity. Beyond bipolar disorder, ongoing investigations are exploring the potential applications of Lithium L-lactate in neuropsychiatric conditions, including studies related to depression, anxiety, and schizophrenia, highlighting its significance in the areas of metabolomics and biochemical research.

Application

Lithium L-lactate has been used as a standard:
  • for the quantification of lactic acid using analytical methods
  • for the quantification of lactic acid using high-performance liquid chromatography
  • as a standard for L-lactic acid assay

Lithium L-lactate is a versatile compound that finds application in metabolomics and biochemical research.

Features and Benefits

  • Ideal for Metabolomics, Biochemical and Cell Biology research
  • Versatile and adaptable for wide variety of laboratory and research applications

Other Notes

For additional information on our range of Biochemicals, please complete this form.
To gain a comprehensive understanding of our extensive range of Monosaccharides for your research, we encourage you to visit our Carbohydrates Category page.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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