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Merck
CN

L2506

β-Lactoglobulin from bovine milk

≥85% (PAGE), lyophilized powder

Synonym(s):

β-LG, Bos d 5, beta-LG

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About This Item

CAS Number:
UNSPSC Code:
12352202
EC Number:
232-928-9
NACRES:
NA.61
MDL number:
Form:
lyophilized powder
Assay:
≥85% (PAGE)
Biological source:
bovine milk
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biological source

bovine milk

Quality Segment

assay

≥85% (PAGE)

form

lyophilized powder

technique(s)

titration: suitable

UniProt accession no.

storage temp.

2-8°C

Gene Information

bovine ... LGB(280838)

General description

β-Lactoglobulin plays a key role in immune response and modulates IgM levels and cell proliferation. β-Lactoglobulin from bovine is a model system for protein folding studies and denaturation kinetics. Polymorphisms in the β-lactoglobulin modulates bovine milk production and composition.
A member of the lipocalin family, βLg is a small protein of 162 amino acids with a molecular mass of ∼18,400 Da,. It has an eight-stranded β-barrel (strands A-H) succeeded by a three-turn a-helix and a final β-strand (strand I) that forms part of the dimerization interface.
Milk from dairy cows contains the protein β-lactoglobulin (BLG). It naturally occurs in a number of genetic variants, and the most prevalent bovine variants are BLG A and BLG B.

Application

β-Lactoglobulin from bovine milk has been used:
  • for the generation of calibration curve for protein solubility index
  • in acid-base titration
  • as a standard for surface hydrophobicity analysis

β-Lactoglobulin was used in a cytologic assay for diagnosis of food hypersensitivity in patients with irritable bowel syndrome.

Analysis Note

Contains β-lactoglobulins A and B which can be isolated chromatographically.


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Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)



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