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Merck
CN

L2643

α-Lactose monohydrate

suitable for cell culture, BioReagent

Synonym(s):

β-D-Gal-(1→4)-α-D-Glc, 4-O-β-D-Galactopyranosyl-α-D-glucose, Milk sugar

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About This Item

Empirical Formula (Hill Notation):
C12H22O11 · H2O
CAS Number:
Molecular Weight:
360.31
NACRES:
NA.75
PubChem Substance ID:
UNSPSC Code:
12352201
MDL number:
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biological source

bovine milk

Quality Level

product line

BioReagent

assay

≥99% total lactose basis (GC)

form

powder

technique(s)

cell culture | mammalian: suitable

impurities

≤0.05% Glucose, ≤4% β-lactose

solubility

water: 100 mg/mL, clear, colorless

SMILES string

[H]O[H].OC[C@H]1O[C@@H](O[C@H]2[C@H](O)[C@@H](O)[C@@H](O)O[C@@H]2CO)[C@H](O)[C@@H](O)[C@H]1O

InChI

1S/C12H22O11.H2O/c13-1-3-5(15)6(16)9(19)12(22-3)23-10-4(2-14)21-11(20)8(18)7(10)17;/h3-20H,1-2H2;1H2/t3-,4-,5+,6+,7-,8-,9-,10-,11+,12+;/m1./s1

InChI key

WSVLPVUVIUVCRA-KPKNDVKVSA-N

Application

α-Lactose monohydrate has been used:
  • as a component of fraction B of diluent M1 for dilution of ram semen
  • as a component of Platz diluent variant (PDV) for dilution of bottlenose dolphin semen
  • in the preparation of HyQ PF-Chinese hamster ovary (CHO) disaccharide media for the adaptation of CHO cell lines
  • for the preparation of protein-free chemically defined cell culture medium (PFCDM) for the adaptation of human embryonic kidney 293 (HEK293) cells



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Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)



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Articles

Discover the role of carbohydrates in drug delivery, from solubility and stability improvement to advanced controlled-release systems.

Explore how carbohydrates function as excipients and carriers in drug delivery, with insights into mechanisms, case studies, and future trends.


A Thiel et al.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 125, 528-539 (2019-02-06)
3-NOP (3-nitrooxypropanol) reduces enteric methane formation in ruminants. A series of ADME studies in rats, lactating goats and beef cattle was performed. 3-NOP was entirely absorbed from the GIT of rats: approximately 75% of the administered 3-NOP was eliminated as
T R Robeck et al.
Biology of reproduction, 70(5), 1340-1348 (2004-01-09)
Research was conducted to develop an effective method for cryopreserving bottlenose dolphin (Tursiops truncatus) semen processed immediately after collection or after 24-h liquid storage. In each of two experiments, four ejaculates were collected from three males. In experiment 1, three
L Anel et al.
Theriogenology, 60(7), 1293-1308 (2003-09-27)
Glycerol has been the most widely used cryopreservation agent for spermatozoa and a wide range of factors affect its action on sperm viability and fertilizing capacity. We tested three methods for freezing ram semen packed in 0.25 ml straws (final



Global Trade Item Number

SKUGTIN
L2643-500G04061833950289
L2643-5KG04061833950296