L2885
Lymphotoxin-β Receptor/Fc Chimera human
>95% (SDS-PAGE), recombinant, expressed in NSO cells, lyophilized powder, suitable for cell culture
Synonym(s):
TNF R-related protein, TNF RIII
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About This Item
UNSPSC Code:
51111800
MDL number:
biological source
human
recombinant
expressed in NSO cells
assay
>95% (SDS-PAGE)
form
lyophilized powder
mol wt
monomer calculated mol wt 49.6 kDa, 70 kDa by SDS-PAGE (reducing) (due to glycosylation)
packaging
pkg of 100 μg
storage condition
avoid repeated freeze/thaw cycles
technique(s)
cell culture | mammalian: suitable
impurities
endotoxin, tested
UniProt accession no.
storage temp.
−20°C
Gene Information
human ... LTBR(4055)
Biochem/physiol Actions
LTBR (lymphotoxin β receptor) is a receptor for LIGHT (tumor necrosis factor ligand superfamily member 14) and LT (lymphotoxin)-a1β2. It is present in the epithelial, stromal and myeloid cells. LTBR participates in lymphoid organ development and immune homeostasis. It is also involved in the lipopolysaccharide (LPS)-mediated expression of IL (interleukin)-8.
Physical form
Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline.
Analysis Note
The biological activity is measured by the ability of the immobilized LTβR/Fc to bind LTα2/β1 and LTα1/β2 in a functional ELISA.
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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