Skip to Content
Merck
CN

L3398

Luteinizing hormone releasing hormone Fragment 7-10 dihydrochloride

≥97% (HPLC)

Synonym(s):

Leu-Arg-Pro-Gly-NH2, LH-RH Fragment 7-10 dihydrochloride

Sign In to View Organizational & Contract Pricing.

Select a Size

About This Item

Empirical Formula (Hill Notation):
C19H36N8O4 · 2HCl
CAS Number:
75690-75-4
Molecular Weight:
513.46
UNSPSC Code:
12352200
PubChem Substance ID:
24896340
MDL number:
MFCD00133509
Assay:
≥97% (HPLC)

Key Documents

View All Documentation
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist

InChI

1S/C19H36N8O4.ClH/c1-11(2)9-12(20)16(29)26-13(5-3-7-24-19(22)23)18(31)27-8-4-6-14(27)17(30)25-10-15(21)28;/h11-14H,3-10,20H2,1-2H3,(H2,21,28)(H,25,30)(H,26,29)(H4,22,23,24);1H

SMILES string

Cl.CC(C)CC(N)C(=O)NC(CCCNC(N)=N)C(=O)N1CCCC1C(=O)NCC(N)=O

InChI key

JKIOGUIXJNHXTH-UHFFFAOYSA-N

assay

≥97% (HPLC)

storage temp.

−20°C

pictograms

Health hazard
GHS08

signalword

Danger

hcodes

H360

Hazard Classifications

Repr. 1B

Storage Class

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type P3 (EN 143) respirator cartridges

Regulatory Information

新产品
This item has

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
070H0225
070H02251
070H02253
070H02252

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Non-peptidic GnRH receptor antagonists.
Armer RE, Smelt KH.
Current Medicinal Chemistry, 11, 33017-33028 (2004)
R P Millar et al.
British medical bulletin, 56(3), 761-772 (2001-03-20)
Gonadotropin-releasing hormone (GnRH) is a decapeptide (pGlu-His-Trp-Ser-Tyr-Gly-Leu-Arg-Pro-Gly.NH2) which is produced from a precursor polypeptide in hypothalamic neurons and secreted in a pulsatile fashion to stimulate the secretion of LH and FSH via its interaction with a cognate receptor on gonadotropes.
Sudhir N Umathe et al.
Behavioural pharmacology, 19(4), 308-316 (2008-07-16)
The correlation between neuronal mechanism of anxiety and neuroanatomic expression/neuromodulatory role of gonadotropin-releasing hormone (GnRH), points to a role of GnRH in the modulation of anxiety. Therefore, we investigated the influence of GnRH agonists and antagonist on the anxiety-like behavior
V Singh
Biochemistry and cell biology = Biochimie et biologie cellulaire, 64(12), 1372-1377 (1986-12-01)
Immunochemical studies on monoclonal and conventional anti-LHRH antibodies have been reported. The association constants (Ka) were in the order of 10(9)-10(10) L/mol when calculated from Scatchard and Steward-Petty plots. Heterogeneity indices (a) calculated from Sips plot were nearly 1.0, indicating

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service