L3625
α-Lactose monohydrate
≥99% total lactose basis (GC)
Synonym(s):
β-D-Gal-(1→4)-α-D-Glc, 4-O-β-D-Galactopyranosyl-α-D-glucose, Milk sugar
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About This Item
Empirical Formula (Hill Notation):
C12H22O11 · H2O
CAS Number:
Molecular Weight:
360.31
NACRES:
NA.25
PubChem Substance ID:
UNSPSC Code:
12352201
MDL number:
biological source
bovine milk
Quality Level
assay
≥99% total lactose basis (GC)
form
powder
impurities
≤0.05% Glucose, ≤4% β-lactose
color
white to off-white
mp
219 °C ((426 °F ))
solubility
water: 100 mg/mL, clear, colorless
storage temp.
room temp
SMILES string
[H]O[H].OC[C@H]1O[C@@H](O[C@H]2[C@H](O)[C@@H](O)[C@@H](O)O[C@@H]2CO)[C@H](O)[C@@H](O)[C@H]1O
InChI
1S/C12H22O11.H2O/c13-1-3-5(15)6(16)9(19)12(22-3)23-10-4(2-14)21-11(20)8(18)7(10)17;/h3-20H,1-2H2;1H2/t3-,4-,5+,6+,7-,8-,9-,10-,11+,12+;/m1./s1
InChI key
WSVLPVUVIUVCRA-KPKNDVKVSA-N
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Application
- Crystal size, a key character of lactose crystallization affecting microstructure, surface chemistry and reconstitution of milk powder.: This study uses alpha-lactose monohydrate as a standard to investigate how crystal size affects the physical properties of milk powder, which is crucial for optimizing production processes in the dairy industry (Qi X et al., 2024).
- Predicting the Strength of Cohesive and Adhesive Interparticle Interactions for Dry Powder Inhalation Blends of Terbutaline Sulfate with alpha-Lactose Monohydrate.: Explores the critical role of alpha-lactose monohydrate, as an excipient together with terbutaline sulfate in optimizing particle interactions for enhanced performance of inhalable therapeutics (Ma CY et al., 2023).
- Terahertz time-domain spectroscopy for the investigation of tablets prepared from roller compacted granules.: This research utilizes alpha-lactose monohydrate to examine the properties of pharmaceutical tablets, offering insights into material characteristics that affect drug delivery systems (Anuschek M et al., 2023).
Biochem/physiol Actions
Lactose is a dissacharide formed by the condensation of one galactose and one glucose molecule. Lactose is the major sugar in the milk of most species, typically present between 2-8%.
alpha-Lactose is the primary sugar present in milk and the main energy source to a newborn mammalian through its mother′s milk. It is digested by the intestinal lactase (EC 3.2.1.108), an enzyme expressed in newborns. The enzyme′s activity declines following weaning which can lead to lactose intolerance in adult mammals.
Other Notes
To gain a comprehensive understanding of our extensive range of Disaccharides for your research, we encourage you to visit our Carbohydrates Category page.
Storage Class
11 - Combustible Solids
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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Gwenola Le Dréan et al.
Nutrients, 11(9) (2019-08-24)
Oligosaccharides (OS) are commonly added to infant formulas, however, their physiological impact, particularly on adult health programming, is poorly described. In adult animals, OS modify microbiota and stimulate colonic fermentation and enteroendocrine cell (EEC) activity. Since neonatal changes in microbiota
Johannes Gursch et al.
Journal of pharmaceutical sciences, 104(10), 3481-3489 (2015-07-07)
Over the last years, continuous manufacturing has created significant interest in the pharmaceutical industry. Continuous filtration at low flow rates and high solid loadings poses, however, a significant challenge. A commercially available, continuously operating, dynamic cross-flow filtration device (CFF) is
Helena Montanuy et al.
Clinical cancer research : an official journal of the American Association for Cancer Research, 26(12), 3044-3057 (2020-02-02)
Fanconi anemia rare disease is characterized by bone marrow failure and a high predisposition to solid tumors, especially head and neck squamous cell carcinoma (HNSCC). Patients with Fanconi anemia with HNSCC are not eligible for conventional therapies due to high
Sha Liu et al.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 96, 132-142 (2015-07-30)
Co-administration of an inhaled corticosteroid and long acting beta agonist for chronic obstructive pulmonary disease has reduced mortality compared to either drug alone. This combination reduces exacerbations, hospitalization, emergency department visits and health care costs. A novel fixed-dose combination of
Global Trade Item Number
| SKU | GTIN |
|---|---|
| L3625-5KG | 04061833951194 |
| L3625-1KG | 04061835438006 |
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