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L3750

β-Lactose

Name: β-Lactose
Brand: SIGMA

≤30% α-anomer basis, ≥99% total lactose basis

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Synonym(s):

β-D-Gal-(1→4)-β-D-Glc

Empirical Formula (Hill Notation):

C₁₂H₂₂O₁₁

CAS Number:

5965-66-2

Molecular Weight:

342.30

EC Number:

227-751-9

MDL number:

MFCD00064521

PubChem Substance ID:

24896352

NACRES:

NA.25

biological source

bovine milk

Assay

≥99% total lactose basis

form

powder

concentration

≥30% (α-anomer)

color

white to off-white

solubility

water: 50 mg/mL, clear, colorless

storage temp.

room temp

SMILES string

OC[C@H]1O[C@@H](O[C@H]2[C@H](O)[C@@H](O)[C@H](O)O[C@@H]2CO)[C@H](O)[C@@H](O)[C@H]1O

InChI

1S/C12H22O11/c13-1-3-5(15)6(16)9(19)12(22-3)23-10-4(2-14)21-11(20)8(18)7(10)17/h3-20H,1-2H2/t3-,4-,5+,6+,7-,8-,9-,10-,11-,12+/m1/s1

InChI key

GUBGYTABKSRVRQ-DCSYEGIMSA-N

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Carbohydrates for Biochemical Research

General description

Lactose is an important disaccharide in human nutrition, culinary goods, and pharmaceuticals. β-lactose is an isomeric form that is rarely found in nature.

Application

β-Lactose has been used:

to treat HL-1 cells followed by phorbol dibutyrate (PDB) treatment to study if protein kinase C (PKC) -stimulated accumulation is mediated through galectin-3
as a component of a media to analyze the extracellular production of protein
along with recombinant galectin-3 to treat cells for the detection of galectin-3 cell surface binding
along with recombinant galectin-3 or a control protein to stimulate T cells for apoptosis assay

Biochem/physiol Actions

Beta-Lactose is the beta-pyranose form of the compound lactose.

Lactose, an excipient in a various medication, is used as an additive in a variety of foods. It is utilized as a commercial additive in the food industry due to its texture, flavor, and adhesive characteristics.

Other Notes

To gain a comprehensive understanding of our extensive range of Disaccharides for your research, we encourage you to visit our Carbohydrates Category page.

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Thrane C, et al.

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Preparation and characterization of high purity anhydrous beta-Lactose from alpha-Lactose monohydrate at mild temperature

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The SARS-CoV-2 pandemic has created an unprecedented need for rapid diagnostic testing to enable the efficient treatment and mitigation of COVID-19. The primary diagnostic tool currently employed is reverse transcription polymerase chain reaction (RT-PCR), which can have good sensitivity and

Galectin-9 regulates the threshold of B cell activation and autoimmunity.

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Despite the mechanisms of central and peripheral tolerance, the mature B cell compartment contains cells reactive for self-antigen. How these cells are poised not to respond and the mechanisms that restrain B cell responses to low-affinity endogenous antigens are not

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