L4131
Lanthanum(III) chloride heptahydrate
≥99.9%
Synonym(s):
Lanthanum trichloride heptahydrate
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About This Item
Linear Formula:
LaCl3 · 7H2O
CAS Number:
Molecular Weight:
371.37
UNSPSC Code:
12352302
MDL number:
InChI key
FDFPDGIMPRFRJP-UHFFFAOYSA-K
InChI
1S/3ClH.La.7H2O/h3*1H;;7*1H2/q;;;+3;;;;;;;/p-3
SMILES string
O.O.O.O.O.O.O.Cl[La](Cl)Cl
assay
≥99.9%
mp
91 °C (dec.) (lit.)
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Biochem/physiol Actions
Calcium channel blocker
signalword
Danger
hcodes
Hazard Classifications
Aquatic Chronic 2 - Eye Dam. 1 - Met. Corr. 1 - Skin Sens. 1
Storage Class
8B - Non-combustible corrosive hazardous materials
wgk
WGK 2
flash_point_f
does not flash
flash_point_c
does not flash
ppe
dust mask type N95 (US), Eyeshields, Gloves
Regulatory Information
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J E Huettner et al.
Neuropharmacology, 37(10-11), 1239-1247 (1998-12-16)
The effects of lanthanum and gadolinium on currents evoked by excitatory amino acids were studied in cultured rat hippocampal and cortical neurons, in freshly dissociated dorsal root ganglion neurons, and in human embryonic kidney 293 cells expressing the GluR6 kainate
Anna Citta et al.
Journal of inorganic biochemistry, 117, 18-24 (2012-10-20)
Lanthanum chloride (LaCl(3)) is a good inhibitor of both the cytosolic and mitochondrial thioredoxin reductase with IC(50) values of 1.75 and 7.46 μM, respectively. On the contrary, the related enzyme glutathione reductase is not inhibited by lanthanum ions even at
Paola Ciceri et al.
Biochemical and biophysical research communications, 418(4), 770-773 (2012-02-09)
Phosphate (Pi)-binders are commonly used in dialysis patients to control high Pi levels, that associated with vascular calcification (VC). The aim of this study was to investigate the effects of lanthanum chloride (LaCl(3)) on the progression of high Pi-induced VC
Mario Pink et al.
Electrophoresis, 34(4), 501-504 (2012-11-30)
The recent introduction of the La(3+) precipitation method for the enrichment of phosphoproteins allows a gel-based analysis of these posttranslationally modified proteins. However, if this method is applied to cell lysates stored in urea-containing lysis buffer for an extended period
Yasuhiko Suzuki et al.
Biochemical and biophysical research communications, 410(2), 317-321 (2011-06-15)
Bradykinin (BK), a mediator of pain and inflammation, is involved in bone metabolism. We have previously reported that BK increased the synthesis of interleukin-6 and prostaglandin E(2) via phosphorylation of ERK1/2 in human osteoblasts, SaM-1. In the present study, we
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