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L5139

Lycorine hydrochloride

Name: Lycorine hydrochloride
Brand: SIGMA

powder, ≥98% (TLC)

Synonym(s):

Licorin hydrochloride, Lychorine chloride, Lycorine HCl

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About This Item

Empirical Formula (Hill Notation):

C₁₆H₁₇NO₄ · HCl

CAS Number:

2188-68-3

Molecular Weight:

323.77

UNSPSC Code:

12352202

PubChem Substance ID:

24896395

NACRES:

NA.77

MDL number:

MFCD00243111

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Properties

Product Name

Lycorine hydrochloride, ≥98% (TLC), powder

Quality Segment

100

assay

≥98% (TLC)

form

powder

mp

210-212 °C

solubility

ethanol: 10 mg/mL, clear, colorless to very faintly yellow

storage temp.

2-8°C

SMILES string

Cl.O[C@H]1C=C2CCN3Cc4cc5OCOc5cc4[C@H]([C@@H]1O)[C@@H]23

InChI

1S/C16H17NO4.ClH/c18-11-3-8-1-2-17-6-9-4-12-13(21-7-20-12)5-10(9)14(15(8)17)16(11)19;/h3-5,11,14-16,18-19H,1-2,6-7H2;1H/t11-,14-,15+,16+;/m0./s1

InChI key

VUVNTYCHKZBOMV-NVJKKXITSA-N

Description

Biochem/physiol Actions

A selective inhibitor of peptidyl transferase center (PTC).

A selective inhibitor of peptidyl transferase center (PTC). In HL-60 (leukemia) cells, lycorine arrests the cell cycle at G2/M and induces apoptosis by a caspase-mediated pathway.

Disclaimer

Protect from light.

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pictograms

GHS06

signalword

Danger

hcodes

H301

pcodes

P264 - P270 - P301 + P310 - P405 - P501

Hazard Classifications

Acute Tox. 3 Oral

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c