L7140
S-Lactoylglutathione
≥90% (TLC)
Synonym(s):
SLG
Sign In to View Organizational & Contract Pricing.
Select a Size
Change View
About This Item
Empirical Formula (Hill Notation):
C13H21N3O8S
CAS Number:
Molecular Weight:
379.39
NACRES:
NA.26
PubChem Substance ID:
UNSPSC Code:
12352209
MDL number:
assay
≥90% (TLC)
form
powder
color
white
application(s)
detection
storage temp.
−20°C
SMILES string
C[C@H](O)C(=O)SC[C@H](NC(=O)CC[C@H](N)C(O)=O)C(=O)NCC(O)=O
InChI
1S/C13H21N3O8S/c1-6(17)13(24)25-5-8(11(21)15-4-10(19)20)16-9(18)3-2-7(14)12(22)23/h6-8,17H,2-5,14H2,1H3,(H,15,21)(H,16,18)(H,19,20)(H,22,23)/t6-,7-,8-/m0/s1
InChI key
VDYDCVUWILIYQF-FXQIFTODSA-N
General description
Suitable for use as a substrate for glyoxalase II.
Application
- Untargeted metabolomics provide new insights into the implication of Lactobacillus helveticus strains isolated from natural whey starter in methylglyoxal-mediated browning.: This research utilizes untargeted metabolomics to investigate the role of S-lactoylglutathione in the browning reaction mediated by methylglyoxal, highlighting its implications in food processing and safety (Galimberti S et al., 2023).
- Multi-omics analysis reveals the molecular regulatory network underlying the prevention of Lactiplantibacillus plantarum against LPS-induced salpingitis in laying hens.: The study identifies the role of S-lactoylglutathione in the regulatory network that prevents LPS-induced salpingitis, emphasizing its importance in avian health and biotechnology applications (Song D et al., 2023).
- Analysis of Glyoxal- and Methylglyoxal-Derived Advanced Glycation End Products during Grilling of Porcine Meat.: This study examines the formation of advanced glycation end products (AGEs) derived from glyoxal and methylglyoxal, focusing on the role of S-lactoylglutathione in mitigating these reactions during meat grilling (Eggen MD et al., 2021).
Biochem/physiol Actions
S-Lactoylglutathione (SLG) is used to study the glutathione-dependent glyoxalase system and KefGB potassium efflux pump in bacteria and plants. S-Lactoylglutathione may also be used to study the inhibition of de novo pyrimidine synthesis in cancer.
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
Storage Class
11 - Combustible Solids
wgk
WGK 3
ppe
dust mask type N95 (US), Eyeshields, Gloves
Choose from one of the most recent versions:
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.
Nathan F Wenzel et al.
Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry, 9(4), 429-438 (2004-04-07)
Cytosolic glyoxalase 2 (GLX2-2) from Arabidopsis thaliana is a metalloenzyme that has been shown to bind a mixture of Zn, Fe, or Mn when produced in cells grown in rich media. In an effort to prepare metal-enriched samples, GLX2-2 was
A Klimes et al.
Canadian journal of microbiology, 52(9), 816-822 (2006-11-18)
A glyoxalase I gene homologue (VdGLO1) was identified in the vascular wilt fungus Verticillium dahliae by sequence tag analysis of genes expressed during resting structure development. The results of the current study show that the gene encodes a putative 345
Tobias Baumann et al.
Nature immunology, 21(5), 555-566 (2020-04-25)
Regulatory myeloid immune cells, such as myeloid-derived suppressor cells (MDSCs), populate inflamed or cancerous tissue and block immune cell effector functions. The lack of mechanistic insight into MDSC suppressive activity and a marker for their identification has hampered attempts to
Ananda Mustafiz et al.
Methods in molecular biology (Clifton, N.J.), 639, 95-118 (2010-04-14)
Glyoxalase system consists of two enzymes glyoxalase I (Gly I) and glyoxalase II (Gly II). Gly I detoxifies methylglyoxal (MG), a cytotoxic byproduct of glycolysis, to S-lactoylglutathione (SLG) where it uses one molecule of reduced glutathione. Subsequently, SLG is converted
Kwang Sik Suh et al.
Free radical research, 52(6), 712-723 (2018-05-25)
Methylglyoxal (MG) is a reactive α-oxoaldehyde that increases under diabetic conditions and subsequently contributes to the complications associated with this disease. Piceatannol is a naturally occurring analogue of resveratrol that possesses multiple biological functions. The present study investigated the effects
Global Trade Item Number
| SKU | GTIN |
|---|---|
| L7140-25MG | 04061833965375 |
| L7140-100MG | 04061833965368 |
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.
Contact Technical Service