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L8045

Liquiritin

from Glycyrrhizae root (licorice root), ≥98% (HPLC)

Synonym(s):

4′,7-Dihydroxyflavanone 4′-glucoside, Liquiritoside

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About This Item

Empirical Formula (Hill Notation):
C21H22O9
CAS Number:
551-15-5
Molecular Weight:
418.39
UNSPSC Code:
12352200
NACRES:
NA.25
MDL number:
MFCD00210526
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biological source

Glycyrrhizae root (licorice root)

Quality Segment

100

assay

≥98% (HPLC)

form

powder

application(s)

metabolomics
vitamins, nutraceuticals, and natural products

storage temp.

2-8°C

SMILES string

O=C1C2=CC=C(O)C=C2O[C@H](C3=CC=C(O[C@H]4[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O4)C=C3)C1

InChI

1S/C21H22O9/c22-9-17-18(25)19(26)20(27)21(30-17)28-12-4-1-10(2-5-12)15-8-14(24)13-6-3-11(23)7-16(13)29-15/h1-7,15,17-23,25-27H,8-9H2/t15-,17+,18+,19-,20+,21+/m0/s1

InChI key

DEMKZLAVQYISIA-ZRWXNEIDSA-N

General description

Liquiritin is a type of flavone, present as an active ingredient in Glycyrrhiza uralensis and Glycyrrhiza glabra extract. It is a constituent of many traditional Chinese medicine formulas popularly used as a cure for asthma, peptic ulcers, and cough.

Application

Liquiritin has been used to analyze the extract of Glycyrrhiza uralensis and examine its components for anti-Hepatitis C virus activity.

Biochem/physiol Actions

Liquiritin has been attributed to show antidepressant-like and antioxidant activity. It causes apoptosis in cell lines having gastric cancer and promyelocytic leukemia. Liquiritin also demonstrates neurotrophic effects and hence has been considered as a potential contender for the management of different neurodegenerative diseases. It shows an anti-inflammatory property with protection to the liver against oxidative damage. It has depigmenting ability and is a potential medicine for melasma.

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Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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