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L8775

Sigma-Aldrich

Lectin from Galanthus nivalis (snowdrop)

agarose conjugate, saline suspension

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Synonym(s):
Galanthus nivalis lectin, GNL
MDL number:

conjugate

agarose conjugate

Quality Level

form

saline suspension

extent of labeling

2-4 mg protein per mL

matrix

cross-linked 4% beaded agarose

capacity

5-10 mg/mL binding capacity (yeast mannan)(pH7.2 at 25 °C)

storage temp.

2-8°C

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Biochem/physiol Actions

GNL agglutinates rabbit erythrocytes; human erythrocytes are not agglutinated. GNL sugar specificity is directed to the nonreducing end of the terminal α-D-mannosyl residue of glycoconjugates.

Physical form

Suspension in 1.0 M NaCl containing 15mM Sodium Azide.

Storage Class Code

10 - Combustible liquids

WGK

WGK 3


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Reda Rawi et al.
Cell reports, 33(8), 108432-108432 (2020-11-26)
Soluble envelope (Env) trimers, stabilized in a prefusion-closed conformation, can elicit neutralizing responses against HIV-1 strains closely related to the immunizing trimer. However, to date such stabilization has succeeded with only a limited number of HIV-1 strains. To address this

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