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L8783

α-Lactose monohydrate

Name: α-Lactose monohydrate
Brand: SIGMA

≥99% total lactose basis (GC), BioXtra

Synonym(s):

β-D-Gal-(1→4)-α-D-Glc, 4-O-β-D-Galactopyranosyl-α-D-glucose, Milk sugar

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About This Item

Empirical Formula (Hill Notation):

C₁₂H₂₂O₁₁ · H₂O

CAS Number:

5989-81-1

Molecular Weight:

360.31

NACRES:

NA.25

PubChem Substance ID:

57654339

UNSPSC Code:

12352201

MDL number:

MFCD00150747

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Properties

Quality Segment

200

biological source

bovine milk

product line

BioXtra

assay

≥99% total lactose basis (GC)

form

powder

impurities

≤0.01% Phosphorus (P), ≤0.1% Insoluble matter

ign. residue

≤0.1%

color

white to off-white

mp

219 °C ((426 °F ))

solubility

H₂O: 1 M, clear, colorless

anion traces

chloride (Cl^-): ≤0.05%, sulfate (SO₄^2-): ≤0.05%

cation traces

Al: ≤0.0005%, Ca: ≤0.005%, Cu: ≤0.0005%, Fe: ≤0.0005%, K: ≤0.02%, Mg: ≤0.0005%, NH₄⁺: ≤0.05%, Na: ≤0.005%, Pb: ≤0.001%, Zn: ≤0.0005%

SMILES string

[H]O[H].OC[C@H]1O[C@@H](O[C@H]2[C@H](O)[C@@H](O)[C@@H](O)O[C@@H]2CO)[C@H](O)[C@@H](O)[C@H]1O

InChI

1S/C12H22O11.H2O/c13-1-3-5(15)6(16)9(19)12(22-3)23-10-4(2-14)21-11(20)8(18)7(10)17;/h3-20H,1-2H2;1H2/t3-,4-,5+,6+,7-,8-,9-,10-,11+,12+;/m1./s1

InChI key

WSVLPVUVIUVCRA-KPKNDVKVSA-N

Description

Application

Insights into the potential of rheological measurements in development of dry powder inhalation formulations.: This article investigates rheological properties and their implications in the development of inhalation formulas where a-Lactose monohydrate plays a crucial role (Almansour et al., 2022).

Spray-Congealing and Wet-Sieving as Alternative Processes for Engineering of Inhalation Carrier Particles: Comparison of Surface Properties, Blending and In Vitro Performance.: The study provides a comparative analysis of spray-congealing and wet-sieving processes in engineering carrier particles for inhalation, utilizing a-Lactose monohydrate (Pinto et al., 2021).

Conversion of a-lactose monohydrate to anhydrous form with superior tabletability by twin-screw extrusion at elevated temperature.: Discusses a method for converting a-Lactose monohydrate to a more compressible anhydrous form, enhancing its application in tablet manufacturing (Batra et al., 2020).

Biochem/physiol Actions

alpha-Lactose is the primary sugar present in milk and the main energy source to a newborn mammalian through its mother′s milk. It is digested by the intestinal lactase (EC 3.2.1.108), an enzyme expressed in newborns. The enzyme′s activity declines following weaning which can lead to lactose intolerance in adult mammals.

Other Notes

To gain a comprehensive understanding of our extensive range of Disaccharides for your research, we encourage you to visit our Carbohydrates Category page.

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Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c