L8920
Lipodisq®
Styrene:Maleic Anhydride Copolymer 2:1
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About This Item
NACRES:
NA.25
UNSPSC Code:
12352202
Form:
powder
Biological source:
synthetic
Application
Lipodisq® has been used in nanoparticle preparation along with palmitoyloleoylphosphatidylcholine (POPC) and palmitoyloleoyl phosphatidylglycerol (POPG).
Lipodisq® reagents are novel polymers derived from styrene and maleic acid. Lipodisq polymers are capable of forming nanosized lipid-based discoidal particles capable of incorporating membrane proteins. The Lipodisq technology can solubilize commonly used lipids such as dimyristoylphosphatidylcholine (DMPC) without the use of detergents. In general, Lipodisq polymers are potentially useful in mitigating the use of detergents for the solubilization of membrane proteins. Lipodisqs typically have a diameter of 9-10 nm at pH 7.4.
Biochem/physiol Actions
Lipodisq® is detergent-free and is useful in membrane protein biophysical studies including electron microscopy (EM), circular dichroism (CD), electron paramagnetic resonance (EPR) and nuclear magnetic resonance (NMR) techniques as well as delivery vehicle.
Legal Information
Lipodisq is a registered trademark of Malvern Cosmeceutics Limited
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Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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