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Merck
CN

L9170

Lipodisq®

Styrene: Maleic Anhydride Copolymer 3:1, Pre-hydrolyzed, powder, from synthetic

Synonym(s):

Lipid nanoparticle, Liposomal delivery system

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About This Item

NACRES:
NA.26
UNSPSC Code:
12352202
Form:
powder
Assay:
98-100%
Biological source:
synthetic
Mol wt:
9500 Da
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biological source

synthetic

Quality Segment

assay

98-100%

form

powder

mol wt

9500 Da

storage condition

(Keep container tightly closed in a dry and well-ventilated place
Keep in a dry place)

storage temp.

room temp

General description

Research area: Cell Structure

Lipodisq® polymers contain styrene and maleic acid monomer units. This product is the pre-hydrolyzed form of the SMA polymer, with styrene and maleic acid monomers. These polymer-lipid complexes are mainly generated by detergent-free methods.

Functional pH range: 6.0 - 9.0

Application

Lipodisq® reagents are novel polymers derived from styrene and maleic acid. Lipodisq polymers are capable of forming nanosized lipid-based discoidal particles capable of incorporating membrane proteins. The Lipodisq technology can solubilize commonly used lipids such as dimyristoylphosphatidylcholine (DMPC) without the use of detergents. In general, Lipodisq polymers are potentially useful in mitigating the use of detergents for the solubilization of membrane proteins. Lipodisqs typically have a diameter of 9-10 nm at pH 7.4.

Legal Information

Lipodisq is a registered trademark of Malvern Cosmeceutics Limited


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Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable



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