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Merck
CN

L9530

Linoleic Acid-Albumin from bovine serum albumin

liquid, sterile-filtered, BioReagent, suitable for cell culture

Synonym(s):

Linoleic Acid-Albumin from BSA

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About This Item

UNSPSC Code:
12352202
NACRES:
NA.75
Form:
liquid
Technique(s):
cell culture | mammalian: suitable
Impurities:
≤400 EU/mL endotoxin
Concentration:
100 mg/mL BSA in DPBS
90-120 mg/mL protein (biuret)

Key Documents

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Product Name

Linoleic Acid-Albumin from bovine serum albumin, liquid, sterile-filtered, BioReagent, suitable for cell culture

description

Contains 2 moles linoleic acid per mole BSA

sterility

sterile-filtered

product line

BioReagent

form

liquid

concentration

100 mg/mL BSA in DPBS
90-120 mg/mL protein (biuret)

technique(s)

cell culture | mammalian: suitable

impurities

≤400 EU/mL endotoxin

storage temp.

2-8°C

Quality Level

300

Related Categories

Application

Linoleic Acid-Albumin from bovine serum albumin is used in the cell line culture and cell differentiation medium.
Linoleic Acid-Albumin from bovine serum albumin is used in the cell line culture and cell differentiation medium.

General description

Fatty Acid-Albumin - complexes have been employed as alternative sources of lipids in the development of serum-free media. Fatty acids bind to serum proteins in high proportions. Such proteins may release beneficial fatty acids and bind those that are inhibitory. Linoleic acid, a precursor of prostaglandins bound to BSA is beneficial to the growth of a variety of cell types (e.g., BHK, hybridoma). It also improves its stability and solubility in culture media.

Other Notes

Recommended usage: 1 ml/100 ml medium

Storage Class

10 - Combustible liquids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves

Regulatory Information

动植物来源生物产品
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Certificates of Analysis (COA)

Lot/Batch Number
0000395772
0000395772
SLCN7396
SLCN7396
SLCD6847

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Chiu-Fang Liang et al.
IUBMB life, 54(5), 275-279 (2003-02-18)
Epidermal growth factor (EGF) was reported to regulate triacyl glycerol synthesis in various cells. Linoleic acid and its metabolites were thought to modulate the signal transduction of growth factors. This study determined whether linoleic acid regulated the effect of EGF
Dong-Hwan Kim et al.
Lipids, 55(2), 163-171 (2020-02-15)
The regulation of adipocyte differentiation is an important factor for production efficiency and meat quality in the poultry industry. The purpose of this study was to develop a new in vitro model of adipogenic differentiation of chicken embryonic fibroblasts (CEF).
Doreen Reichert et al.
Cells, 10(4) (2021-05-01)
Chronic liver diseases are associated with excessive deposition of extracellular matrix proteins. This so-called fibrosis can progress to cirrhosis and impair vital functions of the liver. We examined whether the receptor tyrosine kinase (RTK) class III inhibitor Crenolanib affects the
Li-Ping Liu et al.
Cell reports, 27(2), 455-466 (2019-04-11)
Induced pluripotent stem cells (iPSCs) are a promising melanocyte source as they propagate indefinitely and can be established from patients. However, the in vivo functions of human iPSC-derived melanocytes (hiMels) remain unknown. Here, we generated hiMels from vitiligo patients using a three-dimensional
Cécile Coste et al.
PloS one, 12(7), e0177962-e0177962 (2017-07-07)
Adult neural crest stem-derived cells (NCSC) are of extraordinary high plasticity and promising candidates for use in regenerative medicine. Several locations such as skin, adipose tissue, dental pulp or bone marrow have been described in rodent, as sources of NCSC.
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Articles

Linoleic acid in Cell Culture

Importance and uses of linoleic acid in serum-free eukaryotic, including hybridoma and Chinese Hamster Ovary (CHO) cell, cultures

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