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L9650

Lithium chloride

Name: Lithium chloride
Brand: SIGMA

Molecular Biology, ≥99%

Synonym(s):

LiCl

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About This Item

Linear Formula:

LiCl

CAS Number:

7447-41-8

Molecular Weight:

42.39

NACRES:

NA.31

PubChem Substance ID:

24896459

UNSPSC Code:

12352302

EC Number:

231-212-3

MDL number:

MFCD00011078

Assay:

≥99%

Grade:

Molecular Biology

Form:

powder

Solubility:

H₂O: 100 mg/mL at 20 °C, clear, colorless

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grade

Molecular Biology

Quality Level

200

assay

≥99%

form

powder

mp

605 °C (lit.)

solubility

H₂O: 100 mg/mL at 20 °C, clear, colorless

anion traces

sulfate (SO₄^2-): ≤0.01%

cation traces

Ba: ≤0.003%, Fe: ≤0.001%, K: ≤0.01%, Na: ≤0.20%, heavy metals (as Pb): ≤0.002%

foreign activity

DNase, NICKase, RNase, protease, none detected

SMILES string

[Li+].[Cl-]

InChI

1S/ClH.Li/h1H;/q;+1/p-1

InChI key

KWGKDLIKAYFUFQ-UHFFFAOYSA-M

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Related Categories

Lab Chemicals

Metals

Salts

Application

Lithium chloride has been used:

in the preparation of wash buffer for chromatin immunoprecipitation
in 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide (MTT) assay
to treat aged myoblast as glycogen synthase kinase (GSK) inhibitor to analyse its effect on wingless/tailess (wnt) signaling

May be used to selectively precipitate RNA.

Biochem/physiol Actions

Lithium chloride has the ability to block glycogen synthase kinase (GSK). It may also possess anti-inflammatory effects at low and non-toxic concentrations.

pictograms

GHS07

signalword

Warning

hcodes

H302,H315,H319

pcodes

P264 - P280 - P301 + P312 - P302 + P352 - P305 + P351 + P338 - P332 + P313

Hazard Classifications

Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2

Storage Class

13 - Non Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

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mTOR and neuroinflammation

Molecules to Medicine with mTOR, 317-329 (2016)

A laboratory practical illustrating the use of the ChIP-qPCR method in a robust model: Estrogen receptor alpha immunoprecipitation using Mcf-7 culture cells

Lacazette E

Biochemistry and Molecular Biology Education, 45(2), 152-160 (2017)

Wnt10b deficiency promotes coexpression of myogenic and adipogenic programs in myoblasts

Vertino AM, et al.

Molecular Biology of the Cell, 16(4), 2039-2048 (2005)

Laforin negatively regulates cell cycle progression through glycogen synthase kinase 3beta-dependent mechanisms

Liu R, et al.

Molecular and cellular biology, 28(23), 7236-7244 (2008)

Wnt affects symmetry and morphogenesis during post-embryonic development in colonial chordates.

Alessandro Di Maio et al.

EvoDevo, 6, 17-17 (2015-07-15)

Wnt signaling is one of the earliest and most highly conserved regulatory pathways for the establishment of the body axes during regeneration and early development. In regeneration, body axes determination occurs independently of tissue rearrangement and early developmental cues. Modulation

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Global Trade Item Number

SKU	GTIN
L9650-100G	04061833966839
L9650-500G	04061833966846

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