L9895
Lectin from Pseudomonas aeruginosa
lyophilized powder
Synonym(s):
PA-I
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About This Item
Form:
lyophilized powder
Product Name
Lectin from Pseudomonas aeruginosa, lyophilized powder
form
lyophilized powder
potency
<15 μg/mL per mL agglutination activity
storage temp.
−20°C
Quality Level
Related Categories
Analysis Note
Agglutination activity is expressed in μg/ml and is determined from serial dilutions of a 1 mg/ml solution using phosphate buffered saline, pH 7.0. This activity is the lowest concentration to agglutinate a 2% suspension of neuraminidase treated human blood group A erythrocytes after one hr incubation at 25 °C.
Highly purified.
Biochem/physiol Actions
PA-I has a major affinity for D-galactose and its derivatives. PA-I agglutinates all types of human and animal erythrocytes and interacts also with unicellular protozoa, algae and bacteria. PA-I induces mitogenic stimulation in cultured human lymphocytes pretreated with neuraminidase.
Packaging
Package size based on protein content. Vial content based on protein by biuret.
Physical form
Lyophilized powder containing approx. 80% protein (biuret), balance primarily sodium citrate, plus traces of calcium chloride, magnesium chloride and manganese chloride
Preparation Note
Purified by affinity chromatography using a modification of Gilboa-Garber.1
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Regulatory Information
常规特殊物品
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Alessandro Palmioli et al.
Chembiochem : a European journal of chemical biology, 20(23), 2911-2915 (2019-06-20)
Biofilm formation by bacterial pathogens is a hallmark of chronic infections and is associated to increased antibiotic tolerance that makes pathogens difficult to eradicate with conventional antibiotic therapies. Infections caused by Pseudomonas aeruginosa are of great concern, especially for immunocompromised
Akiko Chiba et al.
Molecular cancer research : MCR, 18(1), 130-139 (2019-10-20)
Breast tumors have their own specific microbiota, distinct from normal mammary gland tissue. Patients with breast cancer that present with locally advanced disease often undergo neoadjuvant chemotherapy to reduce tumor size prior to surgery to allow breast conservation or limit
Articles
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