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LGCC400CH10

CopyCutter EPI400 Chemically Competent E. coli

pkg of 10 reactions (10 x 50 µL), Cfu/μg > 1 x 107

Synonym(s):

Competent Cells

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About This Item

UNSPSC Code:
41106202
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biological source

Escherichia coli

manufacturer/tradename

Lucigen C400CH10

packaging

pkg of 10 reactions (10 x 50 µL)

growth mode

growth or suspension

technique(s)

microbiological culture: suitable

cell transformation

competent cell type: chemically competent
transformation efficiency: 1×107 cfu/μg

shipped in

dry ice

storage temp.

-65 to -96°C

General description

CopyCutter EPI400TM E.coli cells were developed to stabilize toxic inserts and cloning toxic unstable DNA.

CopyCutter EPI400TM E.coli cells significantly lower the copy number of a wide variety of popular high copy number vectors to maintain “toxic” genes or unstable DNA sequences in the vectors.

The CopyCutter EPI400TM E.coli Induction Solution is provided to induce to higher copy number for improved plasmid yield.

Application

Cloning of unstable DNA sequences; Cloning of expressing toxic proteins

Features and Benefits

  • Optimized for cloning toxic or unstable DNA
  • Stabilize toxic inserts in common cloning and expression vectors (pUC and pET-type vectors)
  • Maintain clones at a low-copy number, then induce to higher copy number for improved plasmid yield
  • Avoid T1 and T5 phage contamination with tonA mutation
  • Choose chemically competent cells (LGCC400CH10) for general cloning or electrocompetent cells (LGCC400EL10) for demanding applications such as library generation
Transformation efficiency: ≥ 1 x 107 (cfu/µg pUC DNA)

Genotype: CopyCutetr EPI400: F- mcrA Δ(mrr-hsdRMS-mcrBC) Φ80dlacZΔM15 ΔlacX74 recA1 endA1 araD139 Δ(ara, leu)7697 galU galK λ- rpsL (StrR) nupG trfA tonA pcnB4 dhfr

Components:

CopyCutter EPI400 Chemically Competent Cells

pUC 19 Trasformation Control

CopyControl Induction Solution

Regulatory Information

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