Skip to Content
Merck
CN

Key Documents

View All Documentation

M0880

Ethyl methanesulfonate

liquid

Synonym(s):

Ethyl mesylate, Methanesulfonic acid ethyl ester

Sign In to View Organizational & Contract Pricing.

Select a Size

Change View

About This Item

Linear Formula:
CH3SO3CH2CH3
CAS Number:
62-50-0
Molecular Weight:
124.16
UNSPSC Code:
12352108
NACRES:
NA.25
PubChem Substance ID:
24896575
EC Number:
200-536-7
Beilstein/REAXYS Number:
773969
MDL number:
MFCD00007559
Form:
liquid
Quality level:
200
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist

form

liquid

Quality Level

200

refractive index

n20/D 1.418 (lit.)

bp

85-86 °C/10 mmHg (lit.)

density

1.206 g/mL at 20 °C

SMILES string

CCOS(C)(=O)=O

InChI

1S/C3H8O3S/c1-3-6-7(2,4)5/h3H2,1-2H3

InChI key

PLUBXMRUUVWRLT-UHFFFAOYSA-N

Looking for similar products? Visit Product Comparison Guide

Application

Ethyl methanesulfonate had been used for inducing mutation in mouse embryonic fibroblasts, yeast human embryonic kidney cell lines and human lymphocytes.

Biochem/physiol Actions

Ethyl methanesulfonate is a DNA ethylating agent, mutagenic to plants and animals and carcinogenic in mammals. It has been used as a model alkylating agent in studies of DNA repair processes. EMS induces base substitutions of guanine-cytosine (G/C) to adenine-thymine (A/T). EMS also generates point mutations and single nucleotide polymorphisms in genomes. EMS is potential chemical mutagen used for inducing mutation in rice, wheat and Arabidopsis thaliana.

pictograms

Health hazardExclamation mark
GHS08,GHS07

signalword

Danger

Hazard Classifications

Acute Tox. 4 Oral - Carc. 1B - Eye Irrit. 2 - Muta. 1B - Repr. 2 - Skin Irrit. 2 - Skin Sens. 1

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

flash_point_f

212.0 °F

flash_point_c

100 °C

ppe

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
BCCN4500
BCCM2053
BCCK9762
BCCH1105
BCCF0900

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Yu-Long Gao et al.
Journal of integrative plant biology, 62(2), 165-180 (2019-01-31)
Targeting-induced local lesions in genomes (TILLING) is a powerful reverse-genetics tool that enables high-throughput screening of genomic variations in plants. Although TILLING has been developed for many diploid plants, the technology has been used in very few polyploid species due
A Rapid and Precise Mutation-Activated Fluorescence Reporter for Analyzing Acute Mutagenesis Frequency
Birnbaum MD, et al.
Cell Chemical Biology (2018)
The effects of thymol on sister chromatid exchange, chromosome aberration and micronucleus in human lymphocytes
Buyukleyla M and Rencuzogullari E
Ecotoxicology and Environmental Safety, 72(3), 943-947 (2009)
Kamel El Omari et al.
Nature communications, 10(1), 846-846 (2019-02-21)
Lipid membrane fusion is an essential function in many biological processes. Detailed mechanisms of membrane fusion and the protein structures involved have been mainly studied in eukaryotic systems, whereas very little is known about membrane fusion in prokaryotes. Haloarchaeal pleomorphic
Jinzhu Li et al.
Genes, 11(11) (2020-10-30)
Lateral root development is a complex process regulated by numerous factors. An important role for sugar in lateral root development has been known for a while, but the underlying molecular basis still remains unclear. In this study, we first showed
View All Related Papers

Articles

Carcinogenesis and Epigenetics

Cancer research has revealed that the classical model of carcinogenesis, a three step process consisting of initiation, promotion, and progression, is not complete.

Global Trade Item Number

SKUGTIN
M0880-10G04061837841064
M0880-1G04061834037521
M0880-5G04061837841071
M0880-25G04061834037538
M0880-100G04061837841057

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service