M1555
MAHMA NONOate
Synonym(s):
6-(2-Hydroxy-1-methyl-2-nitrosohydrazino)-N-methyl-1-hexanamine, NOC-9
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About This Item
Empirical Formula (Hill Notation):
C8H20N4O2
CAS Number:
Molecular Weight:
204.27
MDL number:
UNSPSC Code:
12352106
PubChem Substance ID:
NACRES:
NA.25
Quality Level
shipped in
dry ice
storage temp.
−70°C
SMILES string
[H][N+]([H])(C)CCCCCCN(C)N([O-])N=O
InChI
1S/C8H19N4O2/c1-9-7-5-3-4-6-8-11(2)12(14)10-13/h9H,3-8H2,1-2H3/q-1/p+1
InChI key
WASRCWNCCFPNEJ-UHFFFAOYSA-O
Application
NO donor
Biochem/physiol Actions
NO release: t1/2 = 3 min (phosphate buffer at 22° C)
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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Mauricio Di Fulvio et al.
American journal of physiology. Heart and circulatory physiology, 284(5), H1686-H1692 (2003-01-11)
Nitric oxide (NO) donors regulate KCl cotransport (KCC) activity and cotransporter-1 and -3 (KCC1 and KCC3) mRNA expression in sheep erythrocytes and in primary cultures of rat vascular smooth muscle cells (VSMCs), respectively. In this study, we used NONOates as
A M Vincent et al.
Journal of neurobiology, 40(2), 171-184 (1999-07-21)
Neuronal injury is intricately linked to the activation of three distinct neuronal endonucleases. Since these endonucleases are exquisitely pH dependent, we investigated in primary rat hippocampal neurons the role of intracellular pH (pH(i)) regulation during nitric oxide (NO)-induced toxicity. Neuronal
Zhao Zhong Chong et al.
Current neurovascular research, 2(3), 197-211 (2005-09-27)
Metabotropic glutamate receptors (mGluRs) are expressed throughout the mammalian central nervous system and integrate a host of signal transduction pathways that determine cellular function, plasticity and injury. Yet, one of the more unique regulatory functions of this family of GTP-binding
J F Leikert et al.
FEBS letters, 506(2), 131-134 (2001-10-10)
4,5-Diaminofluorescein (DAF-2) and its membrane-permeable derivate DAF-2 diacetate are fluorescent probes that have been developed to perform real-time biological detection of nitric oxide (NO). Their use for intracellular imaging, however, has recently been seriously questioned and data using DAF-2 for
S H Lin et al.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 20(9), 1380-1391 (2000-09-20)
Neuronal injury may be dependent upon the generation of the free radical nitric oxide (NO) and the subsequent induction of programmed cell death (PCD). Although the nature of this injury may be both preventable and reversible, the underlying mechanisms that
Articles
Nitric oxide (NO) as a signal transporter in neurons, endothelial cells and in the immune system.
一氧化氮 (NO) 是神经元、内皮细胞和免疫系统中的信号转运分子。
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