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M2069

D-(+)-Mannose

Name: <SC>D</SC>-(+)-Mannose
Brand: SIGMA

≥99% (GC), wood

Synonym(s):

D-Mannopyranose

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About This Item

Empirical Formula (Hill Notation):

C₆H₁₂O₆

CAS Number:

3458-28-4

Molecular Weight:

180.16

UNSPSC Code:

12352201

NACRES:

NA.25

PubChem Substance ID:

24896601

EC Number:

222-392-4

Beilstein/REAXYS Number:

1564373

MDL number:

MFCD00064122

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biological source

wood

Quality Level

200

assay

≥99% (GC)

form

powder

technique(s)

gas chromatography (GC): suitable

color

white to off-white

mp

133-140 °C (lit.)

solubility

water: 50 mg/mL, clear, colorless to faintly yellow

storage temp.

room temp

SMILES string

OC[C@H]1OC(O)[C@@H](O)[C@@H](O)[C@@H]1O

InChI

1S/C6H12O6/c7-1-2-3(8)4(9)5(10)6(11)12-2/h2-11H,1H2/t2-,3-,4+,5+,6?/m1/s1

InChI key

WQZGKKKJIJFFOK-QTVWNMPRSA-N

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Related Categories

Biochemicals

Carbohydrates for Biochemical Research

Cell Culture Supplements & Reagents

Chemical Biology

General description

Mannose is a monosaccharide.

Application

D-Mannose has been used in a study to assess the synthesis of a family of amphiphilic glycopolymers. It has also been used in a study to investigate the early detection of bronchiolitis obliterans after lung transplantation.

D-(+)-Mannose, a C-2 epimer of D-glucose, is used in the formation of glycan structure and glycosylation.

Biochem/physiol Actions

Mannose, a six-carbon carbohydrate, is the C-2 epimer of glucose and a critical sugar for protein glycosylation. Mannose can also be utilized by the brain as an alternative energy source.

Analysis Note

Predominantly α-isomer

Other Notes

From spruce, birch, or beech wood

To gain a comprehensive understanding of our extensive range of Monosaccharides for your research, we encourage you to visit our Carbohydrates Category page.

Storage Class

11 - Combustible Solids

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Regulatory Information

涉药品监管产品

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Synthesis of a family of amphiphilic glycopolymers via controlled ring-opening polymerization of functionalized cyclic carbonates and their application in drug delivery.

Fabian Suriano et al.

Biomaterials, 31(9), 2637-2645 (2010-01-16)

Polymers bearing pendant carbohydrates have a variety of biomedical applications especially in the area of targeted drug delivery. Here we report the synthesis of a family of amphiphilic block glycopolymers containing d glucose, d galactose and d mannose via metal-free

Internalization and endosomal degradation of receptor-bound antigens regulate the efficiency of cross presentation by human dendritic cells.

Bithi Chatterjee et al.

Blood, 120(10), 2011-2020 (2012-07-14)

Dendritic cells (DCs) can capture extracellular antigens and load resultant peptides on to MHC class I molecules, a process termed cross presentation. The mechanisms of cross presentation remain incompletely understood, particularly in primary human DCs. One unknown is the extent

Increased plasma mannose binding lectin levels are associated with bronchiolitis obliterans after lung transplantation.

Steven J Budd et al.

Respiratory research, 13, 56-56 (2012-07-06)

Long-term lung allograft survival is limited by bronchiolitis obliterans syndrome (BOS). Mannose binding lectin (MBL) belongs to the innate immune system, participates in complement activation, and may predispose to graft rejection. We investigated mannose binding (MBL) during cold ischemia and

M-ficolin binds selectively to the capsular polysaccharides of Streptococcus pneumoniae serotypes 19B and 19C and of a Streptococcus mitis strain.

Troels R Kjaer et al.

Infection and immunity, 81(2), 452-459 (2012-11-28)

The three human ficolins (H-, L-, and M-ficolins) and mannan-binding lectin are pattern recognition molecules of the innate immune system mediating activation of the lectin pathway of the complement system. These four human proteins bind to some microorganisms and may

A CD63 Homolog Specially Recruited to the Fungi-Contained Phagosomes Is Involved in the Cellular Immune Response of Oyster Crassostrea gigas.

Conghui Liu et al.

Frontiers in immunology, 11, 1379-1379 (2020-08-15)

Cluster of differentiation 63 (CD63), a four-transmembrane glycoprotein in the subfamily of tetraspanin, has been widely recognized as a gateway from the infection of foreign invaders to the immune defense of hosts. Its role in Pacific oyster Crassostrea gigas is

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Global Trade Item Number

SKU	GTIN
M2069-5G	04061832384139
M2069-500G	04061834041566
M2069-100G	04061834041542
M2069-25G	04061834041559

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