M2140
1-Decanoyl-rac-glycerol
≥99%
Synonym(s):
Monocaprin
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About This Item
Empirical Formula (Hill Notation):
C13H26O4
CAS Number:
Molecular Weight:
246.34
NACRES:
NA.25
PubChem Substance ID:
UNSPSC Code:
12352211
EC Number:
247-667-6
MDL number:
InChI key
LKUNXBRZDFMZOK-UHFFFAOYSA-N
InChI
1S/C13H26O4/c1-2-3-4-5-6-7-8-9-13(16)17-11-12(15)10-14/h12,14-15H,2-11H2,1H3
SMILES string
O=C(OCC(O)CO)CCCCCCCCC
biological source
synthetic (organic)
assay
≥99%
form
powder
functional group
ketone
lipid type
neutral glycerides
shipped in
ambient
storage temp.
−20°C
Quality Level
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Related Categories
Application
- Novel LC/MS/MS and High-Throughput Mass Spectrometric Assays for Monoacylglycerol Acyltransferase Inhibitors.: This research presents advanced assays for screening inhibitors of monoacylglycerol acyltransferase, with implications for metabolic disease treatment. 1-Decanoyl-rac-glycerol is a key compound in the study (Qi J et al., 2017).
- Optimized reverse micelle surfactant system for high-resolution NMR spectroscopy of encapsulated proteins and nucleic acids dissolved in low viscosity fluids.: The paper describes a novel surfactant system using 1-Decanoyl-rac-glycerol, which improves the NMR spectroscopy of proteins and nucleic acids, offering better resolution and reduced viscosity (Dodevski I et al., 2014).
Biochem/physiol Actions
Monocaprin (glycerol monocaprate) is used in the development of antimicrobial disinfectants active against enveloped viruses, and certain yeast and bacteria such as candida albicans and campylobacter.
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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Skuli Skulason et al.
Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology, 41(1), 61-67 (2011-05-04)
Current treatment of herpes labialis is usually with topical antiviral drugs and early drug administration is required for effectiveness. Monocaprin, a 1-monoglyceride of capric acid, has high microbicidal activity in vitro and efficiently inactivates herpes simplex virus. Tetracyclines are inhibitors
Thórunn O Thorgeirsdóttir et al.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 59(2), 333-342 (2005-01-22)
The purpose of this study was to characterize the rheological and structural properties of a pharmaceutical multicomponent hydrogel formulation. This formulation consists of a hydrogel-forming poly(acrylic acid) polymer (Carbopol 974P), microbicide (monocaprin), non-ionic surfactant (Tween 20 or Tween 40), and
P Reis et al.
Langmuir : the ACS journal of surfaces and colloids, 22(19), 8169-8177 (2006-09-06)
Starting from gold chips, we have tailor-made three surfaces by the self-assembly monolayer technique: one entirely hydrophobic, one hydrophobic with dispersed carboxyl groups, and one hydrophilic, containing hydroxyl groups. Rhizomucor miehei lipase has been adsorbed to the hydrophobic and the
J R Brown et al.
International journal of pharmaceutics, 245(1-2), 133-142 (2002-09-25)
This study explores the potential of the monoglyceride monocaprin as an enhancer of the epithelial permeability of the beta(3)-adrenoceptor agonist BTA-243, as an approach to improving the bioavailability of this drug. The permeabilities of BTA-243 and mannitol (paracellular marker) in
G Bergsson et al.
APMIS : acta pathologica, microbiologica, et immunologica Scandinavica, 109(10), 670-678 (2002-03-14)
The susceptibilities of three Gram-positive cocci to medium-chain saturated and long-chain unsaturated fatty acids and their one-monoglycerides were studied. The bacteria were incubated with equal volumes of lipid solutions for 10 min. Lauric acid, palmitoleic acid and monocaprin reduced the
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