M2521
IgM, Lambda from murine myeloma
clone MOPC 104E, ascites fluid, lyophilized powder
Synonym(s):
Mouse IgM-λ
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About This Item
biological source
mouse
Quality Level
conjugate
unconjugated
antibody form
ascites fluid
clone
MOPC 104E, monoclonal
form
lyophilized powder
storage temp.
2-8°C
General description
The MOPC-104E tumor line that produces mouse IgM is a mineral oil induced plasmacytoma originated and carried intraperitoneally in BALB/c mice. Mouse consists of five immunoglobulin classes- IgM, IgG, IgA, IgD and IgE. IgM is present on the surface of B lymphocytes in its monomeric form.
Application
IgM, λ from murine myeloma has been used as control in chromatin immunoprecipitation analysis. It has also been used in immunohistochemitsry.
IgM, λ from murine myeloma was used as a control antibody in ChIP analysis of GATA-1-null and GATA-1-positive G1E cells.
Biochem/physiol Actions
Antigen Specificity: α(1→3) glucose
IgM antibodies are present as pentamers in the serum and are produced in response to antigens.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Regulatory Information
动物来源生物产品
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Related Content
Datasheet
Molecular Genetics of Immunoglobulin, 17 (1987)
GATA-1-mediated Transcriptional Repression Yields Persistent Transcription Factor IIB-Chromatin Complexes
Martowicz ML, et al.
The Journal of biological chemistry, 281(49), 37345-37352 (2006)
D Chen et al.
The American journal of physiology, 277(3), H1100-H1106 (1999-09-14)
Abnormal proliferation of vascular smooth muscle cells (VSMCs) is thought to play an important role in the pathogenesis of atherosclerosis and restenosis. Previous studies have implicated the extracellular matrix protein thrombospondin-1 (TSP1) in mitogen-dependent proliferation of VSMCs. In this study
Global Trade Item Number
| SKU | GTIN |
|---|---|
| M2521-5MG | 04061833275504 |