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M2672

(±)-α-Methyl-(4-tetrazolylphenyl)glycine

Name: (±)-α-Methyl-(4-tetrazolylphenyl)glycine
Brand: SIGMA

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About This Item

Empirical Formula (Hill Notation):

C₁₀H₁₁N₅O₂

CAS Number:

169209-66-9

Molecular Weight:

233.23

UNSPSC Code:

12352202

PubChem Substance ID:

329817948

MDL number:

MFCD00672653

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Properties

form

solid

storage temp.

2-8°C

SMILES string

CC(N)(C(O)=O)c1ccc(cc1)-n2cnnn2

InChI

1S/C10H11N5O2/c1-10(11,9(16)17)7-2-4-8(5-3-7)15-6-12-13-14-15/h2-6H,11H2,1H3,(H,16,17)

InChI key

PUQSGMIEFYCTSW-UHFFFAOYSA-N

Description

Biochem/physiol Actions

(±)-α-Methyl-(4-tetrazolylphenyl)glycine (MTPG) was used in rat models of cerebral ischemia to explore the role of group II metabotropic glutamate receptors mGluR2/3 in brain ischemia tolerance. MTPG inhibited the induction of ischemia tolerance indicating the involvement of mGluR2/3 in the induction of the protective mechanism.

Potent antagonist for (1S,3S)-ACPD-sensitive receptors; preference for GluR₂ and GluR₃ subtypes

Storage Class

13 - Non Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Regulatory Information

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Certificates of Analysis (COA)

Lot/Batch Number

066H0243

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Global Trade Item Number

SKU	GTIN
M2672-5MG	04061832948164
M2672-1MG	04061823206907