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M2939

Methyl arachidonyl fluorophosphonate

Name: Methyl arachidonyl fluorophosphonate
Brand: SIGMA

≥98%, calcium-dependent and calcium-independent cytosolic phospholipase A2 inhibitor, methyl acetate solution (10 mg/mL)

Synonym(s):

MAPF, Phosphonofluoridic acid, methyl-5Z,8Z,11Z,14Z-eicosatetraenyl ester

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About This Item

Empirical Formula (Hill Notation):

C₂₁H₃₆FO₂P

CAS Number:

188404-10-6

Molecular Weight:

370.48

NACRES:

NA.77

PubChem Substance ID:

329817956

UNSPSC Code:

41106300

EC Number:

201-185-2

MDL number:

MFCD03095722

Assay:

≥98%

Form:

methyl acetate solution (10 mg/mL)

Quality level:

200

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Product Name

Methyl arachidonyl fluorophosphonate, ≥98%, methyl acetate solution (10 mg/mL)

Quality Level

200

assay

≥98%

form

methyl acetate solution (10 mg/mL)

shipped in

dry ice

storage temp.

−70°C

SMILES string

CCCCC\C=C/C\C=C/C\C=C/C\C=C/CCCCP(F)(=O)OC

InChI

1S/C21H36FO2P/c1-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20-21-25(22,23)24-2/h7-8,10-11,13-14,16-17H,3-6,9,12,15,18-21H2,1-2H3/b8-7-,11-10-,14-13-,17-16-

InChI key

KWKZCGMJGHHOKJ-ZKWNWVNESA-N

Related Categories

Bioactive Small Molecule Inhibitors

Bioactive Small Molecules

Biochem/physiol Actions

MAFP is a selective, irreversible inhibitor of both calcium-dependent and calcium-independent cytosolic phospholipase A₂, but not secretory phospholipase A₂. MAFP is also a potent acetylcholinesterase inhibitor.

Preparation Note

To change the solvent, evaporate the methyl acetate under a gentle stream of nitrogen and immediately add the solvent of choice.

Disclaimer

Supply conditions do not apply to the regions and states of Brazil: North, Northeast, Mato Grosso do Sul, Mato Grosso, and Rio Grande do Sul.

pictograms

GHS02,GHS07

signalword

Danger

hcodes

H225,H319,H336

pcodes

P210 - P233 - P240 - P241 - P242 - P305 + P351 + P338

Hazard Classifications

Eye Irrit. 2 - Flam. Liq. 2 - STOT SE 3

target_organs

Central nervous system

supp_hazards

EUH066

Storage Class

3 - Flammable liquids

wgk

WGK 2

flash_point_f

3.2 °F - closed cup

flash_point_c

-16 °C - closed cup

ppe

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter

Regulatory Information

危险化学品

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Certificates of Analysis (COA)

Lot/Batch Number

0000454931

0000255050

SLCM7860

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Global Trade Item Number

SKU	GTIN
M2939-5MG	04061838064844

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