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M2946

Mosapride citrate salt dihydrate

Name: Mosapride citrate salt dihydrate
Brand: SIGMA

≥98% (HPLC), solid, 5-HT₄ receptor agonist

Synonym(s):

4-Amino-5-chloro-2-ethoxy-N-[[4-[(4-fluorophenyl)methyl ]-2-morpholinyl]methyl]benzamide citrate dihydrate

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About This Item

Empirical Formula (Hill Notation):

C₂₁H₂₅ClFN₃O₃ · C₆H₈O₇ · 2H₂O

CAS Number:

636582-62-2

Molecular Weight:

650.05

UNSPSC Code:

12352200

PubChem Substance ID:

329817957

NACRES:

NA.77

MDL number:

MFCD00874415

Assay:

≥98% (HPLC)

Form:

solid

Quality level:

100

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Product Name

Mosapride citrate salt dihydrate,

assay

≥98% (HPLC)

Quality Level

100

form

solid

solubility

DMSO: ≥5 mg/mL

originator

Takeda

storage temp.

2-8°C

SMILES string

O.O.OC(=O)CC(O)(CC(O)=O)C(O)=O.CCOc1cc(N)c(Cl)cc1C(=O)NCC2CN(CCO2)Cc3ccc(F)cc3

InChI

1S/C21H25ClFN3O3.C6H8O7.2H2O/c1-2-28-20-10-19(24)18(22)9-17(20)21(27)25-11-16-13-26(7-8-29-16)12-14-3-5-15(23)6-4-14;7-3(8)1-6(13,5(11)12)2-4(9)10;;/h3-6,9-10,16H,2,7-8,11-13,24H2,1H3,(H,25,27);13H,1-2H2,(H,7,8)(H,9,10)(H,11,12);2*1H2

InChI key

KVKIQHMTGSGTFO-UHFFFAOYSA-N

Related Categories

Bioactive Small Molecules

Biochem/physiol Actions

Mosapride is found effective against chronic gastritis, functional dyspepsia and gastro-oesophageal reflux disease. It is useful in treating many other symptoms associated with gastrointestinal disorders. Mosapride is known to improve digestive motility.

5-HT₄ receptor agonist and 5-HT₃receptor antagonist

Features and Benefits

This compound was developed by Takeda. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

pictograms

GHS05

signalword

Danger

hcodes

H318

pcodes

P280 - P305 + P351 + P338

Hazard Classifications

Eye Dam. 1

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

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Mosapride

Curran MP and Robinson DM

Drugs, 68(7), 981-991 (2008)

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Global Trade Item Number

SKU	GTIN
M2946-10MG	04061834046219
M2946-50MG	04061835259755

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