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M3547

Sigma-Aldrich

Mangiferin Mangifera indica

Synonym(s):

1,3,6,7-Tetrahydroxyxanthone C2-β-D-glucoside

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12 EA
CN¥4,167.96

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12 EA
CN¥4,167.96

About This Item

Empirical Formula (Hill Notation):
C19H18O11
CAS Number:
Molecular Weight:
422.34
MDL number:
UNSPSC Code:
12352205
PubChem Substance ID:
NACRES:
NA.25

CN¥4,167.96


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Assay

≥98% (TLC)

Quality Level

form

powder

application(s)

metabolomics
vitamins, nutraceuticals, and natural products

SMILES string

OC[C@H]1O[C@H]([C@H](O)[C@@H](O)[C@@H]1O)c2c(O)cc3Oc4cc(O)c(O)cc4C(=O)c3c2O

InChI

1S/C19H18O11/c20-4-11-15(25)17(27)18(28)19(30-11)12-8(23)3-10-13(16(12)26)14(24)5-1-6(21)7(22)2-9(5)29-10/h1-3,11,15,17-23,25-28H,4H2/t11-,15-,17+,18-,19+/m1/s1

InChI key

AEDDIBAIWPIIBD-ZJKJAXBQSA-N

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This Item
Z101117Z101125Z103837
material

304 stainless steel needle, chrome-plated hub

material

304 stainless steel needle, chrome-plated hub

material

304 stainless steel needle, chrome-plated hub

material

304 stainless steel needle, chrome-plated hub

packaging

pack of 12 ea

packaging

pack of 12 ea

packaging

pack of 12 ea

packaging

pack of 12 ea

manufacturer/tradename

Popper 7059

manufacturer/tradename

Cadence Science 4072

manufacturer/tradename

Cadence Science 4076

manufacturer/tradename

Cadence Science

L

2 in.

L

2 in.

L

3 1/2 in.

L

2 in.

gauge

20

gauge

18

gauge

17

gauge

22

General description

Mangiferin (MGF) is a natural bioactive polyphenol predominantly isolated from the Mangifera indica (Mango) tree.[1] It has a xanthone glucoside structure.[2] Mangiferin can also be found in other angiosperm plants and herbs.[3]

Application

Mangiferin has been used:
  • as a reference standard for the characterization of mangiferin from Mangifera indica using ultrasound with three-phase partitioning (UTPP)[4]
  • to study its effects in promoting brown adipose phenotype murine C3H10T1/2 mesenchymal stem cells (MSCs) and its role in mitochondrial biogenesis and homeostasis[5]
  • as a reference standard for the quantitative determination of markers compounds in the culture Swertia paniculata shoot culture using high-performance thin-layer chromatography (HPTLC)[6]

Biochem/physiol Actions

Mangiferin has various pharmacological properties including antioxidant, anti-diabetic, anti-bacterial, cardioprotective, neuroprotective, and immunomodulatory activities.[1] It has also displayed antidiabetic, antihyperlipidemic, and antiatherogenic properties in streptozotocin-induced diabetic rats.[2] MGF exerts chemotherapeutic and chemo-preventative activities.[7] It displays antioxidant, analgesic, and hepatoprotective activity against carbon tetrachloride-induced liver injury.[8] MGF is a known accelerator of gastrointestinal transit (GIT).[9]

Pictograms

Skull and crossbones

Signal Word

Danger

Hazard Statements

Hazard Classifications

Acute Tox. 1 Oral

Storage Class Code

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

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