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M3778

N-Methyl-N-propargyl-3-(2,4-dichlorophenoxy)propylamine hydrochloride

Name: N-Methyl-N-propargyl-3-(2,4-dichlorophenoxy)propylamine hydrochloride
Brand: SIGMA

≥97% (GC), MAO-A inhibitor, powder

Synonym(s):

Clorgyline

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About This Item

Empirical Formula (Hill Notation):

C₁₃H₁₅Cl₂NO · HCl

CAS Number:

17780-75-5

Molecular Weight:

308.63

NACRES:

NA.77

PubChem Substance ID:

24278179

UNSPSC Code:

12352116

EC Number:

241-760-5

MDL number:

MFCD00052012

Assay:

≥97% (GC)

Form:

powder

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Properties

Product Name

N-Methyl-N-propargyl-3-(2,4-dichlorophenoxy)propylamine hydrochloride, ≥97% (GC)

Quality Segment

100

assay

≥97% (GC)

form

powder

solubility

DMSO: 10 mg/mL, clear, colorless to faintly yellow

storage temp.

2-8°C

SMILES string

Cl.CN(CCCOc1ccc(Cl)cc1Cl)CC#C

InChI

1S/C13H15Cl2NO.ClH/c1-3-7-16(2)8-4-9-17-13-6-5-11(14)10-12(13)15;/h1,5-6,10H,4,7-9H2,2H3;1H

InChI key

BBAZDLONIUABKI-UHFFFAOYSA-N

Gene Information

human ... MAOA(4128)
rat ... Maoa(29253), Maob(25750)

Description

Application

N-Methyl-N-propargyl-3-(2,4-dichlorophenoxy)propylamine hydrochloride has been used as a monoamine oxidase A (MAO-A) inhibitor:

in MAO-A biochemical assay
to study its effects on the transit of serotonin (5-HT) in the human placenta explants
to study its effects on human prostate cancer cells

Biochem/physiol Actions

MAO-A inhibitor.

Features and Benefits

This compound is featured on the Dopamine and Norepinephrine Metabolism page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.