M4008
Morin hydrate
antioxidant, powder
Synonym(s):
2′,3,4′,5,7-Pentahydroxyflavone
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About This Item
Empirical Formula (Hill Notation):
C15H10O7 · xH2O
CAS Number:
Molecular Weight:
302.24 (anhydrous basis)
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12171500
EC Number:
207-542-9
MDL number:
Form:
powder
Product Name
Morin hydrate, powder
form
powder
Quality Segment
color
yellow
solubility
methanol: 50 mg/mL
SMILES string
O.Oc1ccc(c(O)c1)C2=C(O)C(=O)c3c(O)cc(O)cc3O2
InChI
1S/C15H10O7.H2O/c16-6-1-2-8(9(18)3-6)15-14(21)13(20)12-10(19)4-7(17)5-11(12)22-15;/h1-5,16-19,21H;1H2
InChI key
MYUBTSPIIFYCIU-UHFFFAOYSA-N
Application
Morin hydrate has been used:
- to investigate its antitumor functionality using cell viability and apoptosis assay in human cancer cell lines.
- as a fluorescence stain to detect aluminum in motor neurons and lumbar cord.
- to study its protective effect on neuronal hearing loss and on neural stem cells (NSCs) proliferation and differentiation
Biochem/physiol Actions
Morin hydrate is a flavonoid with antioxidant properties. It has been shown to protect cells against oxygen radical damage. Morin not only scavenges oxyradicals, but also moderately inhibits xanthine oxidase, a free-radical generating enzyme. At concentrations of 75-100 micromolar, morin inhibits oxidation of low density lipoprotein (LDL) by free radicals or Cu2+. Morin has been reported to inhibit rat brain phosphatidylinositolphosphate kinase activity in vitro and in vivo.
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signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
Storage Class
11 - Combustible Solids
ppe
dust mask type N95 (US), Eyeshields, Gloves
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