M4155
Anti-Mouse IgG (Fab specific) antibody produced in goat
2.0 mg/mL, affinity isolated antibody
Synonym(s):
Anti-Mouse Fab Antibody, Anti-Mouse Fab Antibody - Anti-Mouse IgG (Fab specific) antibody produced in goat
biological source
goat
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
secondary antibodies
clone
polyclonal
concentration
2.0 mg/mL
technique(s)
Ouchterlony double diffusion: suitable
indirect ELISA: 1:15,000
shipped in
dry ice
storage temp.
−20°C
target post-translational modification
unmodified
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General description
IgG consists of four polypeptide chains, made of two identical 50 kDa γ heavy (H) chains and two identical 25 kDa κ or λ light (L) chains, which are connected by inter-chain disulfide bonds. IgG has four isotypes IgG1, IgG2, IgG3 and IgG4.
Application
Anti-Mouse IgG (Fab specific) antibody produced in goat has been used in the expression and purification of human platelet factor 4 (PF4) and anti-PF4 monoclonal antibodies.
Anti-Mouse IgG (Fab specific) antibody produced in goat was used as secondary antibody in immunocytochemical staining at a dilution of 1:10.
Biochem/physiol Actions
IgG activates the classical pathway of the complement system. It neutralizes virus particles and toxins. IgG plays a critical role in antibody-dependent cell-mediated cytotoxicity (ADCC). It has the longest serum half life and might be associated with allergy.
IgG antibody subtype is the most abundant of serum immunoglobulins of the immune system. It is secreted by B cells and is found in blood and extracellular fluids. It provides protection from infections caused by bacteria, fungi and viruses. Maternal IgG is transferred to fetus through the placenta that is vital for immune defense of the neonate against infections.
Physical form
Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide.
Other Notes
Antibody adsorbed with bovine, equine and human serum proteins.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class Code
12 - Non Combustible Liquids
WGK
WGK 2
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Regulatory Information
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