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M4324

Myelin Oligodendrocyte Glycoprotein (44-54), Rat, Mouse

lyophilized powder

Synonym(s):

MOG (44-54)

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About This Item

Empirical Formula (Hill Notation):
C61H94N20O15
Molecular Weight:
1347.52
NACRES:
NA.32
UNSPSC Code:
12352202
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form

lyophilized powder

Quality Segment

color

white

solubility

deionized water: soluble

UniProt accession no.

storage temp.

−20°C

Gene Information

mouse ... Mog(17441)
rat ... Mog(24558)

Biochem/physiol Actions

The 21-residue peptide MOG 35-55 contains an antigenic epitope responsible for the activation of CD8 encephalitogenic T cells in mice. Two truncated peptides, MOG 40-54 and MOG 44-54 were shown to bind the recombinant H-2Db protein. This complex then binds MOG specific CD8 T cells. While MOG 40-54 retained the full capability of inducing paralytic disease, MOG 44-54 only partialy causes clinical paralysis and central nervous system inflamation.

Physical form

Lyophilized from 0.1% aqueous TFA.

Other Notes

Lyophilized from 0.1% TFA in H2O


Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable



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