M4603
Acetyl-[Nle4, Asp5, D-2-Nal7, Lys10]-cyclo-α-Melanocyte Stimulating Hormone Amide Fragment 4-10
≥95% (HPLC), Melanocortin-4 receptor antagonist
Synonym(s):
SHU9119
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About This Item
Empirical Formula (Hill Notation):
C54H71N15O9
Molecular Weight:
1074.24
UNSPSC Code:
51111800
NACRES:
NA.32
MDL number:
Product Name
Acetyl-[Nle4, Asp5, D-2-Nal7, Lys10]-cyclo-α-Melanocyte Stimulating Hormone Amide Fragment 4-10, ≥95% (HPLC)
Quality Segment
assay
≥95% (HPLC)
UniProt accession no.
storage temp.
−20°C
Gene Information
human ... POMC(5443)
Biochem/physiol Actions
Screening analogs of the cyclic lactam melanocortin agonist MTII led to the identification of the agoutimimetic SHU9119. This compound shares pharmacological properties with the agouti peptide in that it is a potent antagonist of the melanocortin-4 receptor and a less potent antagonist of the melanocortin-3 receptor.
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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