M4750
α-D(+)Mannose 1-phosphate bis(cyclohexylammonium) salt
Synonym(s):
α-D-Mannopyranosyl phosphate
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About This Item
Empirical Formula (Hill Notation):
C6H11O9P · 2C6H14N
CAS Number:
Molecular Weight:
458.48
UNSPSC Code:
12352201
PubChem Substance ID:
MDL number:
InChI
1S/2C6H13N.C6H13O9P/c2*7-6-4-2-1-3-5-6;7-1-2-3(8)4(9)5(10)6(14-2)15-16(11,12)13/h2*6H,1-5,7H2;2-10H,1H2,(H2,11,12,13)/t;;2-,3-,4+,5+,6-/m..1/s1
SMILES string
NC1CCCCC1.NC2CCCCC2.OC[C@H]3O[C@H](OP(O)(O)=O)[C@@H](O)[C@@H](O)[C@@H]3O
InChI key
YBPDNWXTAIIEAM-SHPZNGBNSA-N
assay
>98% (TLC)
form
powder
technique(s)
thin layer chromatography (TLC): suitable
storage temp.
−20°C
General description
Mannose is a monosaccharide.
Application
Mannose has been used in a study to assess the evolutionarily conserved glycan signal that degrades aberrant brassinosteroid receptors in Arabidopsis. It has also been used in a study to investigate preferences for uptake of carbohydrate-coated liposomes by C-type lectin receptors.
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Regulatory Information
涉药品监管产品
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Yoko Kawauchi et al.
Glycoconjugate journal, 29(7), 481-490 (2012-06-27)
We evaluated the carbohydrate preferences of the C-type lectin receptors (CLRs) SIGNR1, SIGNR3, and Langerin as pathogen-uptake receptors based on uptake of liposomes consisting of cholesterol, DPPC, and various neoglycolipids at molar ratios of 10:10:1 and 10:7:4, respectively, using non-phagocytic
Evolutionarily conserved glycan signal to degrade aberrant brassinosteroid receptors in Arabidopsis.
Zhi Hong et al.
Proceedings of the National Academy of Sciences of the United States of America, 109(28), 11437-11442 (2012-06-27)
Asparagine-linked glycans (N-glycans) are crucial signals for protein folding, quality control, and endoplasmic reticulum (ER)-associated degradation (ERAD) in yeast and mammals. Although similar ERAD processes were reported in plants, little is known about their biochemical mechanisms, especially their relationships with
Silvia Guzman-Beltran et al.
Microbes and infection, 14(12), 1093-1101 (2012-07-10)
Sporothrix schenckii is a human pathogen that causes sporotrichosis, a cutaneous subacute or chronic mycosis. Little is known about the innate immune response and the receptors involved in host recognition and phagocytosis of S. schenckii. Here, we demonstrate that optimal
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