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Merck
CN

M4934

Anti-Matrix Metalloproteinase-18, C-Terminal antibody produced in rabbit

~1 mg/mL, affinity isolated antibody, buffered aqueous glycerol solution

Synonym(s):

Anti-Xenopus collagenase, Anti-MMP-18, Anti-MMP-21-A, Anti-XMMP

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41
MDL number:
Conjugate:
unconjugated
Clone:
polyclonal
Application:
ELISA (i), IHC (f), IP, WB
Citations:
-
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biological source

rabbit

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous glycerol solution

species reactivity

Xenopus

concentration

~1 mg/mL

technique(s)

immunohistochemistry (frozen sections): suitable, immunoprecipitation (IP): suitable, indirect ELISA: suitable, western blot: 1:1,000

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Quality Level

Gene Information

Xenopus laevis ... mmp21-A(378572)

Immunogen

synthetic peptide corresponding to the C-terminal of Xenopus matrix metalloproteinase-18 (Xenopus collagenase, collagenase-4).

Biochem/physiol Actions

Reacts with reduced and non-reduced MMP-18. Recognizes pro-form and most active forms of MMP-18. When used against the reduced protein, the antibody identifies bands at 53 kDa and 51 kDa (pro-form) as well as the smaller activated forms. The hemopexin domain is cleaved form the smallest active form of MMP-18 and the antibody does not detect this form.

Physical form

Solution in phosphate buffered saline, pH 7.4, containing 50% glycerol and 15 mM sodium azide

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Storage Class

10 - Combustible liquids

Regulatory Information

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