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Merck
CN

M5170

IgM, Lambda from murine myeloma

clone MOPC 104E, purified immunoglobulin, buffered aqueous solution

Synonym(s):

Mouse IgM-λ

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.46
MDL number:
Conjugate:
unconjugated
Clone:
MOPC 104E, monoclonal
Application:
Citations:
11
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biological source

mouse

Quality Segment

conjugate

unconjugated

antibody form

purified immunoglobulin

clone

MOPC 104E, monoclonal

form

buffered aqueous solution

shipped in

dry ice

storage temp.

−20°C

target post-translational modification

unmodified

General description

IgM antibodies are present as pentamers in the serum and are produced in response to antigens
IgM, λ from murine myeloma is produced by MOPC 104E tumor line introduced subcutaneously in BALB/c mice. It specifically recognizes mouse IgM, λ. Identity and purity of the immunoglobulin is established by immunoelectrophoresis.

Application

IgM, λ from murine myeloma was used as standard in ELISA and as isotype control in immunohistochemistry applications.

Biochem/physiol Actions

IgM antibodies are produced initially during B-cell development. IgM participates in opsonization and compliment fixation. Defect in IgM production is observed in X-linked agammaglobulinemia.
Antigen Specificity: α(1→3) glucose

Physical form

Solution in 0.05 M Tris, 0.5 M sodium chloride, pH 8.0, containing 0.02% sodium azide

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.


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Storage Class

10 - Combustible liquids

wgk

nwg

flash_point_f

Not applicable

flash_point_c

Not applicable



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