M5644
(±)-Methoxyverapamil hydrochloride
≥98%
Synonym(s):
(±)-α-[3-[(2-(3,4-Dimethoxyphenyl)ethyl)methylamino]propyl]-3,4,5-trimethoxy-α-(1-methylethyl)benzeneacetonitrile hydrochloride, D 600, Gallopamil
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About This Item
Empirical Formula (Hill Notation):
C28H40N2O5 · HCl
CAS Number:
Molecular Weight:
521.09
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352200
MDL number:
Assay:
≥98%
Quality Segment
assay
≥98%
SMILES string
Cl[H].COc1ccc(CCN(C)CCCC(C#N)(C(C)C)c2cc(OC)c(OC)c(OC)c2)cc1OC
InChI
1S/C28H40N2O5.ClH/c1-20(2)28(19-29,22-17-25(33-6)27(35-8)26(18-22)34-7)13-9-14-30(3)15-12-21-10-11-23(31-4)24(16-21)32-5;/h10-11,16-18,20H,9,12-15H2,1-8H3;1H
InChI key
OKCRIUNHEQSXFD-UHFFFAOYSA-N
General description
Methoxyverapamil is a calmodulin antagonist. It controls flagellar glycoprotein redistribution by modulating calcium signalling. Methoxyverapamil impacts the effect of intracellular calcium levels and affects the sperm capacitation function.
Application
(±)-Methoxyverapamil hydrochloride has been used:
- as calcium channel antagonist in Schistosoma mansoni parasite
- as calcium entry blocker in cultured macrophages
- in the inhibition of L-type voltage gated Ca2+-channels
Biochem/physiol Actions
Blocks L-type Ca2+ channels
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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Product Information Sheet
Global Trade Item Number
| SKU | GTIN |
|---|---|
| M5644-50MG | 04061834060147 |
| M5644-250MG | 04061834060130 |