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M6020

D-(+)-Mannose

Name: <SC>D</SC>-(+)-Mannose
Brand: SIGMA

powder, BioReagent, suitable for cell culture

Synonym(s):

D-Mannopyranose

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About This Item

Empirical Formula (Hill Notation):

C₆H₁₂O₆

CAS Number:

3458-28-4

Molecular Weight:

180.16

UNSPSC Code:

12352201

NACRES:

NA.75

PubChem Substance ID:

24897068

EC Number:

222-392-4

Beilstein/REAXYS Number:

1564373

MDL number:

MFCD00064122

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biological source

plant (Spruce, Birch or Beech Wood, Glucose)

Quality Level

300

product line

BioReagent

assay

≥99%

form

powder

technique(s)

cell culture | mammalian: suitable

mp

133-140 °C (lit.)

solubility

H₂O: 50 mg/mL

application(s)

advanced drug delivery
agriculture

SMILES string

OC[C@H]1OC(O)[C@@H](O)[C@@H](O)[C@@H]1O

InChI

1S/C6H12O6/c7-1-2-3(8)4(9)5(10)6(11)12-2/h2-11H,1H2/t2-,3-,4+,5+,6?/m1/s1

InChI key

WQZGKKKJIJFFOK-QTVWNMPRSA-N

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Related Categories

Biochemicals

Carbohydrates for Biochemical Research

Cell Culture Supplements & Reagents

Chemical Biology

General description

Mannose is an aldohexose carbohydrate. It is isomer of glucose with varying C2 position configuration. Majority of mannose is synthesised from its epimer glucose. It is part of the glycans present in endoplasmic reticulum (ER)/Golgi.

Application

D-(+)-Mannose has been used:

as a reference standard in monosaccharide analysis and quantification from sea squirts Ascidiella aspersa
as a medium component for the selection of P898012 sorgum seeds transfected with Agrobacterium
in segmented filamentous bacterium (SFB) medium supplement for culturing human cell lines

Mannose is an aldohexose carbohydrate. This product may be used to study the effects of exogenous mannose on in vitro processes such as glycosylation.

Biochem/physiol Actions

Mannose may be used to study the effects of exogenous mannose on in vitro processes such as glycosylation. cis-Golgi glycoproteins have high mannose and are prone to Endoglycosidase H or peptide N-glycosidase (N-glycanase) digestion.

Storage Class

11 - Combustible Solids

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Regulatory Information

涉药品监管产品

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Metabolic manipulation of glycosylation disorders in humans and animal models

Freeze HH and Sharma V

Seminars in Cell & Developmental Biology, 21(6), 655-662 (2010)

Essentials of Carbohydrate Chemistry by John F. Robyt

Pendarvis R

The Chemical Educator, 3(5), 1-2 (1998)

Golgi glycosylation

Stanley P

Cold Spring Harbor Perspectives in Biology, 3(4), a005199-a005199 (2011)

Agrobacterium-mediated transformation of Sorghum bicolor using immature embryos

Transgenic Plants, 109-122 (2012)

Quantitative analysis and virulence phenotypes of atypical enteropathogenic Escherichia coli (EPEC) acquired from diarrheal stool samples from a Midwest US hospital.

M J Carlino et al.

Gut microbes, 12(1), 1-21 (2020-11-03)

Infectious diarrhea causes approximately 179 million illnesses annually in the US. Multiplex PCR assays for enteric pathogens detect enteropathogenic Escherichia coli (EPEC) in 12-29% of diarrheal stool samples from all age groups in developed nations. The aim of this study

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Global Trade Item Number

SKU	GTIN
M6020-100G	04061834518518
M6020-25G	04061835568918
M6020-500G	04061835568925

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