M6680
Se-(Methyl)selenocysteine hydrochloride
≥95% (TLC), apoptosis inducer
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About This Item
Empirical Formula (Hill Notation):
C4H9NO2Se · HCl
CAS Number:
Molecular Weight:
218.54
UNSPSC Code:
12352209
PubChem Substance ID:
NACRES:
NA.32
MDL number:
Product Name
Se-(Methyl)selenocysteine hydrochloride, ≥95% (TLC)
Quality Segment
assay
≥95% (TLC)
storage temp.
−20°C
SMILES string
Cl.C[Se]C[C@H](N)C(O)=O
InChI
1S/C4H9NO2Se.ClH/c1-8-2-3(5)4(6)7;/h3H,2,5H2,1H3,(H,6,7);1H/t3-;/m0./s1
InChI key
JMPVTFHGWJDSDV-DFWYDOINSA-N
General description
Selenium (Se)-(Methyl) selenocysteine (MeSeCys) is a methylated product of selenocysteine, this reaction is catalyzed by selenocysteine methyltransferase (SMT) in Astragalus bisulcatus.
Application
Se-(Methyl) selenocysteine hydrochloride has been used as a standard in fluorescence-XANES (X-ray absorption near-edge spectroscopy) imaging.
Biochem/physiol Actions
Selenium (Se)-(Methyl) selenocysteine functions as a potent chemotherapeutic agent for human breast cancer. Enhanced production of methlylselenol from L-Se-methylselenocysteine in vivo alters redox status of cells and oxidatively triggers cellular apoptosis. It is implicated in inhibition of mammary tumor formation in rats.
Se-(Methyl)selenocysteine is a chemopreventive agent that blocks cell cycle progression and proliferation of premalignant mammary lesions and induces apoptosis of cancer cell lines in culture.
signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - STOT RE 2
Storage Class
6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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