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M6751

5-Methylcytosine hydrochloride

≥99%, synthetic (organic), crystalline powder

Synonym(s):

4-Amino-2-hydroxy-5-methylpyrimidine

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About This Item

Empirical Formula (Hill Notation):
C5H7N3O · HCl
CAS Number:
58366-64-6
Molecular Weight:
161.59
NACRES:
NA.51
PubChem Substance ID:
24897110
UNSPSC Code:
41106305
EC Number:
261-223-9
MDL number:
MFCD11053426
Assay:
≥99%
Biological source:
synthetic (organic)
Form:
crystalline powder
Solubility:
water: 50 mg/mL, clear to slightly hazy, colorless
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Product Name

5-Methylcytosine hydrochloride, ≥99%

biological source

synthetic (organic)

Quality Segment

300

assay

≥99%

form

crystalline powder

solubility

water: 50 mg/mL, clear to slightly hazy, colorless

SMILES string

O=C1NC(N)=C(C)C=N1.[H]Cl

InChI

1S/C5H7N3O.ClH/c1-3-2-7-5(9)8-4(3)6;/h2H,1H3,(H3,6,7,8,9);1H

InChI key

ANWMULVRPAUPJT-UHFFFAOYSA-N

Application

5-Methylcytosine hydrochloride has been used as standard in high performance liquid chromatography (HPLC) for the estimation of global methylation rates. It has also been used in high-resolution mass spectroscopic analysis.
5-Methylcytosine is used in studies of DNA methylation processes (epigenetics).

Biochem/physiol Actions

5-Methylcytosine mediates gene expression, genomic imprinting and inhibition of transposable elements. It is closely associated with translational fidelity and tRNA recognition.

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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