M6779
Small Cardioactive Peptide B
≥97% (HPLC)
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About This Item
Empirical Formula (Hill Notation):
C52H80N14O11S2
CAS Number:
Molecular Weight:
1141.41
UNSPSC Code:
12352200
PubChem Substance ID:
MDL number:
SMILES string
CSCCC(N)C(=O)NC(CC(N)=O)C(=O)NC(Cc1ccc(O)cc1)C(=O)NC(CC(C)C)C(=O)NC(C)C(=O)NC(Cc2ccccc2)C(=O)N3CCCC3C(=O)NC(CCCNC(N)=N)C(=O)NC(CCSC)C(N)=O
assay
≥97% (HPLC)
storage temp.
−20°C
Biochem/physiol Actions
Cardioactive peptide originally isolated from Aplysia.
Storage Class
13 - Non Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Regulatory Information
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S L Hooper et al.
Brain research, 657(1-2), 337-341 (1994-09-19)
Application of small cardioactive peptide (SCP) or stimulation of motorneuron B15 increases the level of activated cAMP-dependent protein kinase (cAPK) in the ARC muscle. SCP application also appears to induce a translocation of cAPK between different subcellular compartments of the
S Sugita et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 17(19), 7237-7244 (1997-09-20)
The synaptic connections between the sensory neurons of Aplysia and their follower neurons have been used as a model system for examining the cellular mechanisms contributing to neuronal and synaptic plasticity. Recent studies suggest that at least two protein kinases
G Reich et al.
Peptides, 18(3), 355-360 (1997-01-01)
Several cardioactive peptides from the pulmonate snail Helix aspersa were tested for their effects on myocardial cAMP levels, but only the family of small cardioactive peptides (SCPs) were clearly effective. SCP increased cAMP in a dose dependent manner; the time
Y Xu et al.
Journal of neurophysiology, 73(3), 1313-1318 (1995-03-01)
1. Serotonin (5-HT), small cardioactive peptide B (SCPB) and FMRFamide have well-established facilitatory and inhibitory effects on sensory neurons and their connections with motor neurons mediating withdrawal reflexes in Aplysia. Little is known, however, about their effects on interneurons contributing
Elucidation by FAB-MS of the structure of a new cardioactive peptide from Aplysia.
H R Morris et al.
Nature, 300(5893), 643-645 (1982-12-16)
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