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M6940

Modafinil

Name: Modafinil
Brand: SIGMA

≥98% (HPLC), Neuroprotective agent, solid

Synonym(s):

2-[(Diphenylmethyl)sulfinyl]acetamide

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About This Item

Empirical Formula (Hill Notation):

C₁₅H₁₅NO₂S

CAS Number:

68693-11-8

Molecular Weight:

273.35

UNSPSC Code:

12352200

PubChem Substance ID:

24897132

NACRES:

NA.77

MDL number:

MFCD00868082

Assay:

≥98% (HPLC)

Form:

solid

Quality level:

100

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Product Name

Modafinil, ≥98% (HPLC)

Quality Level

100

assay

≥98% (HPLC)

form

solid

drug control

USDEA Schedule IV; Új pszichoaktív anyag / New psychoactive substance (Hungary), 78/2022. (XII. 28.) BM rendelet

color

white

solubility

DMSO: >10 mg/mL

originator

Teva

SMILES string

NC(=O)CS(=O)C(c1ccccc1)c2ccccc2

InChI

1S/C15H15NO2S/c16-14(17)11-19(18)15(12-7-3-1-4-8-12)13-9-5-2-6-10-13/h1-10,15H,11H2,(H2,16,17)

InChI key

YFGHCGITMMYXAQ-UHFFFAOYSA-N

Gene Information

human ... SLC6A3(6531)
rat ... Slc6a3(24898)

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Related Categories

Bioactive Small Molecules

Biochem/physiol Actions

Modafinil is a central nervous system vigilance promoting agent, which posseses neuroprotective properties.

Features and Benefits

This compound was developed by Teva. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

pictograms

GHS08,GHS07

signalword

Warning

hcodes

H302,H361d

pcodes

P202 - P264 - P280 - P301 + P312 - P308 + P313 - P405

Hazard Classifications

Acute Tox. 4 Oral - Repr. 2

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Regulatory Information

监管及禁止进口产品

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Certificates of Analysis (COA)

Lot/Batch Number

0000038704

0000207777

0000207778

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Photoperiodic regulation of dopamine signaling regulates seasonal changes in retinal photosensitivity in mice.

Kousuke Okimura et al.

Scientific reports, 11(1), 1843-1843 (2021-01-21)

At high latitudes, approximately 10% of people suffer from depression during the winter season, a phenomenon known as seasonal affective disorder (SAD). Shortened photoperiod and/or light intensity during winter season are risk factors for SAD, and bright light therapy is

Interactions between modafinil and cocaine during the induction of conditioned place preference and locomotor sensitization in mice: implications for addiction.

Tristan Shuman et al.

Behavioural brain research, 235(2), 105-112 (2012-09-12)

Modafinil is a wake-promoting drug effective at enhancing alertness and attention with a variety of approved and off-label applications. The mechanism of modafinil is not well understood but initial studies indicated a limited abuse potential. A number of recent publications

Modafinil disrupts prepulse inhibition in mice: strain differences and involvement of dopaminergic and serotonergic activation.

Perrin Kwek et al.

European journal of pharmacology, 699(1-3), 132-140 (2012-12-12)

Modafinil is a wakefulness-promoting agent with possible beneficial effects for the management of addiction and in psychiatric conditions, but also with abuse potential of its own. The mechanism of action of modafinil remains unclear. We studied pharmacological mechanisms in the

A diagnostic conundrum: acute interstitial nephritis due to armodafinil versus acute cellular rejection in a renal transplant recipient--a case report.

K M Baradhi et al.

Transplantation proceedings, 45(2), 845-847 (2013-03-19)

Acute interstitial nephritis is a well-recognized cause of acute kidney injury in native kidneys. While the most common etiology being drug-induced, other causes are infectious, autoimmune, and idiopathic forms of disease. Drug-induced acute interstitial nephritis is not only uncommon in

Modafinil and armodafinil in schizophrenia.

Chittaranjan Andrade

The Journal of clinical psychiatry, 73(8), e1062-e1064 (2012-09-13)

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Global Trade Item Number

SKU	GTIN
M6940-10MG	04061832557267
M6940-50MG	04061832557274

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