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M8692

Sigma-Aldrich

Anti-Matrix Metalloproteinase-21, Hinge Region antibody produced in rabbit

affinity isolated antibody, buffered aqueous glycerol solution

Synonym(s):

Anti-MMP-21

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About This Item

MDL number:
MFCD03097025
UNSPSC Code:
12352203
NACRES:
NA.41

biological source

rabbit

Quality Level

200

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous glycerol solution

species reactivity

rat, human, Xenopus, mouse

technique(s)

western blot: 1:1,000

UniProt accession no.

Q8N119

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... MMP21(118856)
mouse ... Ighg(380794)

General description

Matrix metalloproteinase-21 (MMP-21) is a secreted protein expressed in fetal tissues, adult tissues and cancer cell lines. It is a 57kDa protein. The gene encoding it is localized on human chromosome 10.

Specificity

By immunoblotting against the reduced protein, the antibody identifies bands at 70 kDa and 66 kDa.

Immunogen

synthetic peptide corresponding to the hinge region of human matrix metalloproteinase-21.

Biochem/physiol Actions

Matrix metalloproteinase-21 (MMP-21) is involved in increasing the invasion capacity and metastasis property of tumors.

Physical form

Solution in 0.01 M phosphate buffered saline containing 50% glycerol and 0.05% sodium azide.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

10 - Combustible liquids

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Certificates of Analysis (COA)

Lot/Batch Number
073K1092

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