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Merck
CN

M9557

Anti-Macrophage Inflammatory Protein-3β antibody produced in goat

affinity isolated antibody, lyophilized powder

Synonym(s):

Anti-MIP-3β

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41
MDL number:
MFCD02096844

Key Documents

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Product Name

Anti-Macrophage Inflammatory Protein-3β antibody produced in goat, affinity isolated antibody, lyophilized powder

biological source

goat

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

lyophilized powder

species reactivity

mouse

technique(s)

immunocytochemistry: 5-15 μg/mL
neutralization: 0.8-4 μg/mL
western blot: 0.1 μg/mL

UniProt accession no.

O70460

storage temp.

−20°C

target post-translational modification

unmodified

Quality Level

200

Gene Information

mouse ... Ccl19(24047)

Related Categories

Biochem/physiol Actions

Macrophage Inflammatory Protein-3β is a chemokine that facilitates the migration of dendritic cells and antigen-presenting cells. It interacts with specific G protein-coupled seven-transmembrane domain chemokine receptor, CCR7 and promotes interactions between T cells and dendritic cells and migration of activated B cells to lymphoid tissues.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

General description

The antibody neutralizes the biological activity of recombinant mouse MIP-3β. Using 50 times more, the antibody will neutralize the biological activity of recombinant human MIP-3β. The antibody shows 5% cross-reactivity with recombinant human MIP-3β.

Immunogen

Recombinant mouse MIP-3β, expressed in Escherichia coli.

Physical form

Lyophilized from 0.2 um-filtered solution in phosphate buffered saline, pH 7.4 with 5% Trehalose

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Storage Class

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

常规特殊物品
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Certificates of Analysis (COA)

Lot/Batch Number
MKCX7333
MKCX2510
MKCW2516
MKCM9149
MKCM0840

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Jian-mei Hou et al.
Acta pharmacologica Sinica, 30(3), 355-363 (2009-03-06)
Tumor immunotherapy aims at activating the body's own immune system to fight an existing tumor. Effective antitumor responses require tumor antigens to be presented to lymphocytes. We aimed to test the hypothesis that intratumoral administration of recombinant adenovirus encoding MIP3beta

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