MAK005
Phenylalanine Assay Kit
sufficient for 100 fluorometric tests
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About This Item
NACRES:
NA.84
UNSPSC Code:
12161503
usage
sufficient for 100 fluorometric tests
detection method
fluorometric
relevant disease(s)
neonatal diseases; neurological disorders; pediatric diseases
storage temp.
−20°C
General description
Phenylalanine is a non-polar essential amino acid. In the liver, phenylalanine is converted to tyrosine, which is a precursor for multiple compounds including L-DOPA and melanin. Defects in the activity of phenylalanine hydroxylase result in the inherited metabolic disorder phenylketonuria (PKU). PKU results in the build up of phenylalanine and phenylalanine metabolites, and can result in growth defects and mental retardation if not treated.
Application
Suitable for L-phenylalanine detection in cell and tissue culture supernatants, serum, and other biological samples
Biochem/physiol Actions
Phenylalanine concentration is determined by a coupled enzyme assay, which results in the deamination of phenylalanine and the production of NADH which reacts with the probe resulting in a fluorescent (λex = 535 nm/λem = 587 nm) product, proportional to the phenylalanine present.
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signalword
Danger
hcodes
pcodes
Hazard Classifications
Resp. Sens. 1
Storage Class
10 - Combustible liquids
flash_point_f
No data available
flash_point_c
No data available
wgk
WGK 3
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