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MAK063

L-Carnitine Assay Kit

sufficient for 100 colorimetric or fluorometric tests

Synonym(s):

Carnitine Quantification Kit

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About This Item

NACRES:
NA.84
UNSPSC Code:
12161503
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usage

sufficient for 100 colorimetric or fluorometric tests

detection method

colorimetric, fluorometric

storage temp.

−20°C

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General description

Carnitine is a metabolite that is synthesized from lysine and methionine. Carnitine is essential for fatty acid β-oxidation due to its role in fatty acid transport into the mitochondrial matrix via the carnitine/acylcarnitine shuttle. Carnitine exists in two stereoisomers but only the L-carnitine isomer is biologically active. Tissue levels of L-carnitine decrease with aging and decreased L-carnitine may contribute to age-related mitochondrial decline. The L-Carnitine Assay Kit is a simple convenient means of measuring free L-Carnitine in biological samples such as serum.

Application

L-Carnitine Assay Kit has been used to determine the concentration of carnitine in serum samples.
Suitable for the measurement of free L-Carnitine in biological samples such as tissue, cells and serum

Biochem/physiol Actions

L-carnitine concentration is determined by a coupled enzyme assay, which results in a colorimetric (570 nm)/ fluorometric (λex = 535/λem = 587 nm) product, proportional to the L-carnitine present. Typical sensitivities of detection for this kit are 10 μM (colorimetric) and 1 μM (fluorometric). The normal range for serum L-Carnitine is between 10-70 μM.

pictograms

Health hazardExclamation mark
GHS08,GHS07

signalword

Danger

target_organs

Respiratory system

Storage Class

10 - Combustible liquids

flash_point_f

188.6 °F - closed cup

flash_point_c

87 °C - closed cup

wgk

WGK 3

Hazard Classifications

Eye Irrit. 2 - Resp. Sens. 1 - Skin Irrit. 2 - STOT SE 3

Regulatory Information

常规特殊物品

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Certificates of Analysis (COA)

Lot/Batch Number
8M12K06420
8M12K06420
7M20K06420
7J07K06420
7D27K06420

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Carnitine modulates crucial myocardial adenosine triphosphatases and acetylcholinesterase enzyme activities in choline-deprived rats
Strilakou A A, et al.
Canadian Journal of Physiology and Pharmacology, 92(1), 78-84 (2013)
Rongli Sun et al.
Environmental toxicology, 35(10), 1033-1042 (2020-06-02)
Widespread occupational and environmental exposure to benzene is unavoidable and poses a public health threat. Studies of potential interventions to prevent or relieve benzene toxicity are, thus, essential. Research has shown l-carnitine (LC) has beneficial effects against various pathological processes
Anna D Kononiuk et al.
Molecules (Basel, Switzerland), 25(10) (2020-05-28)
The present study examined the effect of the type of meat (beef and fallow deer) and the addition of freeze-dried acid whey on nutritional values and the content of bioactive compounds (peptides, L-carnitine, glutathione, and conjugated linoleic acid (CLA)) in
Francesca Pala et al.
Journal of cell science, 131(14) (2018-07-29)
During growth, homeostasis and regeneration, stem cells are exposed to different energy demands. Here, we characterise the metabolic pathways that mediate the commitment and differentiation of mouse skeletal muscle stem cells, and how their modulation can influence the cell state.

Articles

Fatty Acid Synthesis in Cancer Cells

Fatty acid synthesis supports cancer cell proliferation, essential for membrane generation, protein modification, and bioenergetics.

Related Content

Global Trade Item Number

SKUGTIN
MAK063-1KT04061826601426

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