MAK071
Pyruvate Assay Kit
sufficient for 100 colorimetric or fluorometric tests
Synonym(s):
Assay Kit for Pyruvate Detection
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About This Item
NACRES:
NA.84
UNSPSC Code:
12161503
usage
sufficient for 100 colorimetric or fluorometric tests
detection method
colorimetric, fluorometric
relevant disease(s)
gastrointestinal diseases; cancer
storage temp.
−20°C
Gene Information
human ... PKLR(5313), PKM2(5315)
mouse ... PKLR(18770), PKM2(18746)
rat ... PKLR(24651), PKM2(25630)
General description
Pyruvate is a central molecule in metabolism that is used and synthesized through multiple metabolic pathways including glycolysis and the transamination of alanine. Pyruvate may be further oxidized in the citric acid cycle, converted to carbohydrates during gluconeogenesis, or reduced to lactate. High levels of pyruvate are associated with liver disease and genetic disorders. Pyruvate has also been used to stimulate metabolism leading to loss of body weight.
Application
Suitable for measuring pyruvate concentration in various biological samples such as blood, tissues, and culture cells.
Biochem/physiol Actions
Pyruvate concentration is determined by a coupled enzyme assay, which results in a colorimetric (570 nm)/fluorometric (λex = 535/λem = 587 nm) product, proportional to the pyruvate present.
Signal Word
Danger
Hazard Codes
Precautionary Statements
Storage Class
10 - Combustible liquids
WGK
WGK 3
Hazard Classifications
Aquatic Chronic 3 - ED ENV 1 - Resp. Sens. 1 - Skin Sens. 1
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