MAK089
γ-Glutamyltransferase (GGT) Activity Colorimetric Assay Kit
sufficient for 100 colorimetric tests
Synonym(s):
GGT Colorimetric Assay Kit
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About This Item
NACRES:
NA.84
UNSPSC Code:
12161503
usage
sufficient for 100 colorimetric tests
detection method
colorimetric
relevant disease(s)
cardiovascular diseases; neurological disorders; cancer; gastrointestinal diseases
storage temp.
−20°C
Gene Information
human ... GGT1(2678), GGT2(728441), GGT5(2687), GGT6(124975), GGT7(2686)
mouse ... GGT1(14598), GGT5(23887), GGT6(71522), GGT7(207182)
rat ... GGT1(116568), GGT5(29566), GGT6(408206), GGT7(156275)
General description
γ-Glutamyltransferase (GGT, EC 2.3.2.2) is a membrane-bound protein that catalyzes the transfer of -glutamyl moieties to acceptor molecules such as amino acids or peptides. GGT plays a key role in the λ-glutamyl cycle, a critical pathway for glutathione homeostasis as well as the detoxification of xenobiotics. Serum GGT levels can be elevated in many pathophysiological conditions such as cardiovascular disease, chronic liver disease, and metabolic syndrome. Elevated serum levels of GGT can also be indicative of oxidative stress.
Application
γ-Glutamyltransferase (GGT) Activity Colorimetric Assay Kit has been used to assess the activity of γ-glutamyltransferase.
Suitable for the measurement of gamma-glutamyl transferase (GGT) in a variety of samples including tissue, cells and serum
Biochem/physiol Actions
The GGT Activity Colorimetric Assay kit provides a simple and direct procedure for measuring GGT activity in a variety of samples. GGT activity is determined by a coupled enzyme assay, in which the GGT transfers the γ-glutamyl group from the substrate L-γ-Glutamyl-p-nitroanilide, liberating the chromogen p-nitroanilide (pNA, 418 nm) proportional to the GGT present. One unit of GGT is the amount of enzyme that will generate 1.0μmole of pNA per minute at 37 °C.
Features and Benefits
Compatible with high-throughput handling systems.
Storage Class
10 - Combustible liquids
wgk
WGK 3
flash_point_f
188.6 °F - closed cup
flash_point_c
87 °C - closed cup
signalword
Danger
hcodes
Hazard Classifications
Aquatic Chronic 2 - ED ENV 1
Regulatory Information
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Instructions
Global Trade Item Number
| SKU | GTIN |
|---|---|
| MAK089-1KT | 04061834065227 |
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