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About This Item
NACRES:
NA.84
UNSPSC Code:
12161503
usage
sufficient for 100 fluorometric tests
application(s)
pharmaceutical
detection method
fluorometric
relevant disease(s)
gastrointestinal diseases; cardiovascular diseases
storage temp.
2-8°C
Gene Information
human ... LPL(4023)
Related Categories
General description
Lipoprotein lipase (LPL) hydrolyzes triglycerides associated with VLDL.
Application
LPL Activity Assay Kit may be used for detection of LPL activity in plasma samples of patients with hypertriglyceridemia.
Suitable for the measurement of lipoprotein lipase activity in a variety of tissue samples
Biochem/physiol Actions
The LPL Activity Assay Kit includes a non-fluorescent substrate emulsion that becomes intensely fluorescent upon interaction with LPL and pre-hydrolyzed substrate for use as a standard to convert the fluorescence intensity reading to moles of reactant formed (λEx=370 nm/λEm=450 nm). The assay is not specific for LPL and will also detect hepatic lipase activity.
Storage Class
10 - Combustible liquids
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Maria Notarnicola et al.
Lipids in health and disease, 11, 145-145 (2012-11-01)
Lipid metabolism is altered in subjects with liver steatosis. FAS is a key enzyme in de novo lipogenesis and both FAS gene expression and enzymatic activity are primarily regulated by metabolic signals in the liver. Lipoprotein lipase (LPL), the rate-limiting
Prabodh Sadana et al.
International journal of molecular sciences, 21(20) (2020-10-15)
Mice fed a high-fat diet for 12 weeks or longer develop hyperglycemia, insulin resistance, dyslipidemia, and fatty liver. Additionally, a high-fat diet induces inflammation that remodels and affects the anti-inflammatory and antiatherogenic property of the high-density lipoprotein (HDL). However, the
Chaofeng Yang et al.
Nutrition & metabolism, 9(1), 94-94 (2012-10-31)
Endocrine FGF19 and FGF21 exert their effects on metabolic homeostasis through fibroblast growth factor receptor (FGFR) and co-factor betaKlotho (KLB). Ileal FGF19 regulates bile acid metabolism through specifically FGFR4-KLB in hepatocytes where FGFR1 is not significant. Both FGF19 and FGF21
Evemie Dubé et al.
Biology of reproduction, 87(1), 14-14 (2012-05-04)
Knowledge of the consequences of maternal obesity in human placental fatty acids (FA) transport and metabolism is limited. Animal studies suggest that placental uptake of maternal FA is altered by maternal overnutrition. We hypothesized that high maternal body mass index
Ewa Szalowska et al.
Peptides, 32(5), 938-945 (2011-02-22)
GIP receptor knockout mice were shown to be protected from the development of obesity on a high fat diet, suggesting a role of GIP in the development of obesity. In our study we aimed to test the hypothesis if excess
Protocols
Lipoprotein lipase (LPL) hydrolyzes triglycerides associated with VLDL.
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