MAK296
Monoamine Oxidase-B Inhibitor Screening Kit (Fluorometric)
sufficient for 100 fluorometric tests
Synonym(s):
MAO-B Inhibitor Fluorometric Assay Kit
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About This Item
NACRES:
NA.25
UNSPSC Code:
12161503
detection method
fluorometric
relevant disease(s)
neurological disorders
storage temp.
−20°C
General description
The new Monoamine Oxidase (MAO) Inhibitor Screening Kit, MAK520, is now available! Monoamine oxidases (MAO, EC 1.4.3.4) are a family of enzymes that can oxidize a wide variety of endogenous primary amines. Two isoforms, MAO-A and MAO-B, have been identified based on their substrate, inhibitor specificity and tissue localization. MAO-B can oxidize primary amines, but its list of specific substrates (i.e. benzylamine, phenylethylamine) is more limited compared to MAO-A.
Application
Suitable for screening/studying/characterizing MAO-B inhibitors.
Biochem/physiol Actions
This MAO-B Inhibitor Screening Kit offers a rapid, simple, sensitive, and reliable test suitable for high-throughput screening of MAO-B inhibitors. The assay is based on the fluorometric detection of H2O2, one of the byproducts generated during the oxidative deamination of the MAO substrate (tyramine).
Features and Benefits
Compatible with high-throughput handling systems.
signalword
Danger
target_organs
Central nervous system
Storage Class
10 - Combustible liquids
wgk
WGK 3
hcodes
Hazard Classifications
Acute Tox. 4 Oral - Resp. Sens. 1 - STOT SE 3
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